The results of the regression model incorporating absolute values of examined breathing pattern parameters were used to characterise dysfunctional breathing among asthma patients.
The Ti/Ttot variable exhibits a large SE indicating instability of the estimate due to collinearity with other timing-related parameters. Results should be interpreted with caution. ABampinsp: abdominal amplitude during inspiration phase; RCampinsp: ribcage amplitude during inspiration phase; RR: respiratory rate; Te: expiration time; Ti: inspiration time; Ttot: total breath cycle duration. a: significant result at p < 0.05.
Declarations
Acknowledgments
The author thanks the participants for their valuable contribution to this dataset. Also, the author thanks the funders for their financial support of the study, which was part of a series of clinical studies conducted for the successful completion of the author’s doctoral degree. The author thanks his supervisors, Prof. Anne Bruton (Emeritus Professor, University of Southampton) and Prof. Anna Barney (Professor of Biomedical Acoustic Engineering, Faculty of Engineering and the Environment, University of Southampton), for their meticulous guidance and contribution to the author’s PhD work that produced the dataset used for the current secondary analysis. Special thanks also go to Prof. Anna Barney for developing and providing the MATLAB algorithm used to extract the breathing pattern data during the author’s PhD work.
Author contributions
PS: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Resources, Visualization, Writing—original draft. The author read and approved the submitted version.
Conflicts of interest
The author declares that he has no conflicts of interest.
Ethical approval
The study had been approved by the London-Queen Square Ethics Committee (Rec no: 17/LO/1640; IRAS ID: 230295). This study complies with the 2013 Declaration of Helsinki.
Consent to participate
All participants provided a written consent form prior to their participation in the study.
Consent to publication
Patients’ anonymous data were agreed to be published to maintain anonymity and protect individuals’ health data.
Availability of data and materials
The dataset used and analyzed during the current secondary analysis, as presented in the current manuscript, is available from the corresponding author (1st author of this manuscript) on reasonable request at psakkatos@upatras.gr.
Funding
The current study which was part of a series of clinical studies of the author’s doctoral research was funded by the British Lung Foundation and the Wessex Medical Trust [15501/01]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.
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