Specifications of the five Fuc-specific lectins [163]

NumberLectinPreferred binding FucSubstances used for elution
1Lens culinaris agglutininFucα1-6GlcNAcmethyl α-D-mannoside
2Lotus tetragonolobus lectinFucα1-3GlcNAc, Fucα1-3 (Lewis X and Y), sLeXL-Fuc
3Ulex europaeus lectin IFucα1-2Gal β1-4Glc(NAc)L-Fuc
4Aleuria aurantia lectinFucα1-2, Fucα1-3/4, Fucα1-6GlcNAcL-Fuc
5Aspergillus oryzae lectinFucα1-2, Fucα1-3/4, Fucα1-6GlcNAcL-Fuc

Note. Adapted from “Comparison of fucose-specific lectins to improve quantitative AFP-L3 assay for diagnosing hepatocellular carcinoma using mass spectrometry,” by Lee J, Yeo I, Kim Y, Shin D, Kim J, Kim Y, et al. J Proteome Res. 2022;21:1548–57 (https://pubs.acs.org/doi/10.1021/acs.jproteome.2c00196). © 2022, American Chemical Society.