Specifications of the five Fuc-specific lectins [163]
Number | Lectin | Preferred binding Fuc | Substances used for elution |
---|---|---|---|
1 | Lens culinaris agglutinin | Fucα1-6GlcNAc | methyl α-D-mannoside |
2 | Lotus tetragonolobus lectin | Fucα1-3GlcNAc, Fucα1-3 (Lewis X and Y), sLeX | L-Fuc |
3 | Ulex europaeus lectin I | Fucα1-2Gal β1-4Glc(NAc) | L-Fuc |
4 | Aleuria aurantia lectin | Fucα1-2, Fucα1-3/4, Fucα1-6GlcNAc | L-Fuc |
5 | Aspergillus oryzae lectin | Fucα1-2, Fucα1-3/4, Fucα1-6GlcNAc | L-Fuc |
Note. Adapted from “Comparison of fucose-specific lectins to improve quantitative AFP-L3 assay for diagnosing hepatocellular carcinoma using mass spectrometry,” by Lee J, Yeo I, Kim Y, Shin D, Kim J, Kim Y, et al. J Proteome Res. 2022;21:1548–57 (https://pubs.acs.org/doi/10.1021/acs.jproteome.2c00196). © 2022, American Chemical Society.
QC: Conceptualization, Writing—original draft, Writing—review & editing. HL: Writing—original draft, Writing—review & editing. XL: Conceptualization, Writing—original draft, Writing—review & editing, Supervision.
The authors declare that they have no conflicts of interest.
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The work was funded by the Laboratory for Synthetic Chemistry and Chemical Biology Limited under the Health@InnoHK Program by the Innovation and Technology Commission. The Funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
© The Author(s) 2023.