From:  Network pharmacology-based identification of neuroprotective compounds in Phyllanthus amarus for the management of Alzheimer’s and Parkinson’s comorbidity

 Protein-protein interaction network and hub analysis.

RankProteinDegreeBetweenness centralityCloseness centralityMCODE cluster
1STAT3500.22360.4408Cluster 1
2PPARG340.23100.4390Cluster 1
3HSP90AB1340.09180.4000Cluster 1
4HIF1A320.13800.4202Cluster 1
5ESR1320.07930.4000Cluster 1
6GRB2280.05340.3364Cluster 2
7PTGS2260.15240.4030Unclustered
8FYN240.05580.3553Cluster 2
9NFKB1240.05440.4138Cluster 1
10TLR4220.06680.3857Unclustered