Astrocytoma: diffuse astrocytoma IDH mutant; GBMwt: glioblastoma IDH wildtype; LGGwt: low-grade glioma IDH wildtype; Medullo: medulloblastoma; MGMTm: methyl-guanine methyltransferase methylated; Oligo: oligodendroglioma; SMO: smoothened. Data were adapted with permission of the Corresponding Author and Elsevier Book Publishers: Newton HB, Pinho M. Chapter 7 - Next-generation sequencing: overview and application to systemic cancer and brain tumors. In: Newton HB, editor. Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy (Third Edition). Academic Press; 2026. pp. 107–138.
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