Exploration of Immunology

Table 3. Shared pentapeptides of human proteins and membrane proteins of human coronaviruses.

Key autoantigens	Viruses	Pentapeptide sequences	Total shared pentapeptides
APOA-1	SARS-CoV-2	ELKKL*	6
	HCoV-HKU1	TVAKV*, VAKVQ
	HCoV-OC43	LTIIL, FTIVA, TVAKV*
HMGCR	HCoV-OC43	IILTI	1
PCSK9	HCoV-NL63	LVLAL	2
PCSK9	HCoV-229E	LVLAL	2
MMP1	SARS-CoV	GHSLG	1
TNC	HCoV-OC43	WTADE	1
MRP-8	SARS-CoV-2	LKKLL, KKLLE	2
Total			13

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*: allergen pentapeptide; HCoV-229E: human coronavirus 229E; HCoV-HKU1: human coronavirus HKU1; HCoV-NL63: human coronavirus NL63; HCoV-OC43: human coronavirus OC43.

Supplementary materials

The supplementary tables for this article are available at: https://www.explorationpub.com/uploads/Article/file/1003257_sup_1.pdf.

Declarations

Author contributions

LPC: Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing—review & editing. VSG: Methodology, Validation. MVM: Methodology. TAN: Methodology, Writing—original draft. VAS: Methodology. PAS: Methodology. VJU: Data curation, Writing—original draft, Writing—review & editing. TVF: Data curation. MGN: Conceptualization, Formal analysis, Investigation, Methodology, Resources, Software, Visualization, Writing—original draft. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

This study complies with the Declaration of Helsinki (2013), and it was approved by the Local Ethical Committee of the L.G. Sokolov North-Western District Scientific and Clinical Centre, approval number 7 dated Dec 08, 2022.

Consent to participate

Informed consent to participate in the study was obtained from all participants.

Consent to publication

Not applicable.

Availability of data and materials

All relevant data are available from the corresponding author on request (muslimbek.normatov@gmail.com)

Funding

This work was supported by the grant of the Government of the Russian Federation for the state support of scientific research carried out under the supervision of leading scientists, agreement NO. 075-15-2022-1110 dated June 30, 2022. Scientific research was performed at the Laboratory of Microangiopathic Mechanisms of Atherogenesis of St. Petersburg State University. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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