ICIs: immune checkpoint inhibitors; PD-1: programmed death-1; PD-L1: programmed cell death ligand 1; MSI-H/dMMR: microsatellite instability high/deficient mismatch repair; NSCLC: non-small cell lung cancer; TNBC: triple-negative breast cancer; TMB: tumor mutational burdens; TILs: tumor-infiltrating lymphocytes; CTLA-4: cytotoxic T lymphocyte-associated protein 4; CTCs: circulating tumor cells; LAG-3: lymphocyte activation gene-3; MLH1: mutL homolog 1; MSH2: mutS homolog 2; TIGIT: T cell immunoreceptor with Ig and ITIM domains; TAMs: tumor-associated macrophages; Tregs: regulatory T cells.
Declarations
Author contributions
QB, HC, and SW: Writing—original draft. ZT and HT: Conceptualization, Supervision, Writing—review & editing. All authors read and approved the submitted version.
Conflicts of interest
The authors declare that there are no conflicts of interest.
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