This table presents a comparative overview of key clinical trials involving oncolytic viruses, summarizing the virus platform, cancer indication, trial phase, combination strategy (if applicable), and reported outcomes. It highlights the therapeutic landscape of oncolytic virotherapy in solid tumors, with emphasis on immune modulation, synergistic combinations, and objective response rates observed in peer-reviewed studies. HSV-1: herpes simplex virus type 1; T-VEC: talimogene laherparepvec; ORR: objective response rate; OS: overall survival; PFS: progression-free survival; GM-CSF: granulocyte-macrophage colony-stimulating factor; CR: complete response; BCG: Bacillus Calmette-Guérin (intravesical immunotherapy for bladder cancer)
Declarations
Author contributions
AAAA: Conceptualization, Writing—original draft, Writing—review & editing, Data curation. RB: Data curation, Writing—review & editing, Validation, Resource. OG: Writing—original draft, Writing—review & editing, Data curation. All authors have read and agreed to the final version of the manuscript.
Conflicts of interest
The authors declare that they have no conflicts of interest.
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