Exploration of Immunology

From: Conserved envelope protein of nCoV2 as the possible target to design polytope vaccine

Table 5. Computation of epitopes of polytope restricted to a broad range of MHC I in the Indian Asian population using http://tools.iedb.org/population/result/#India%20Asian

Epitope	Coverage	HLA allele [genotypic frequency (%)]						Total HLA hits
Epitope	Class I	*HLA-A01:01 (8.36)**	*HLA-A02:01 (3.81)**	*HLA-A24:02 (11.25)**	*HLA-A31:01 (6.74)**	*HLA-B07:02 (2.29)**	*HLA-B15:01 (3.60)**	Total HLA hits
Epitope #1: RVKNLNSSR	45.68%	+	+	+	+	+	+	6
Epitope #2: YVYSRVKNL	45.68%	+	+	+	+	+	+	6
Epitope #3: LVKPSFYVY	45.68%	+	+	+	+	+	+	6
Epitope #4: SLVKPSFYV	45.68%	+	+	+	+	+	+	6
Epitope #5: YVYSRVKNL	45.68%	+	+	+	+	+	+	6
Epitope set	45.68%	5	5	5	5	5	5	30

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Acknowledgments

The author profusely acknowledges the management of Vignan’s Foundation for Science, Technology and Research (Deemed to be University) for providing the facility through Centre of Excellence and DST FIST Net-working lab (LSI-576/2013).

Author contributions

The author contributed solely to the work. The concept developed and content projected in the present article are original and prepared by the author.

Conflicts of interest

The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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