From:  Metabolic syndrome in menopause

 Hormone replacement to minimize or prevent metabolic syndrome in menopause.

ConditionAdviceComments
Premature ovarian failure or oophorectomy in premenopausal womenHormone replacement until the expected age of menopause
With an intact uterus and ovariesIndividualize treatment*Estradiol valerate patch (1 or 2 mg)
Micronized progesterone
Dydrogesterone
Medicated IUCD

*: Hormone therapy is in addition to lifestyle and behavior interventions to prevent and treat concomitant hypertension, insulin resistance, type 2 diabetes mellitus, dyslipidemia, and obesity: preferably to start early in the perimenopause; rule out contraindications (see main text); must be individualized. IUCD: intrauterine contraceptive device.