Exploration of Cardiology

From: Systemic transthyretin amyloidosis: carpal tunnel syndrome in a Portuguese population (CarPoS)

Table 1. Study design of protocol

Items	Parameters
Type of study	Case-control
Location	Centro Hospitalar Universitário de São João
Patients	Both genders and ≥ 60 years old
Cohorts	Cases: symptomatic CTS and surgical treatment indication
Cohorts	Controls: absence of symptomatic CTS and indication for hand surgical treatment
Exclusion criteria	Patients with diabetes mellitus, hypothyroidism, chronic renal failure under haemodialysis, rheumatoid arthritis and other inflammatory arthropathies, multiple myeloma, gout, chondrocalcinosis, Colles’s fracture, space-occupying lesions, or infectious synovitis

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CTS: carpal tunnel syndrome

Declarations

Author contributions

SP and AM: Conceptualization, Investigation, Writing—original draft, Writing—review & editing. MC, BSP and ASP: Conceptualization. JS and IF: Writing—review & editing. PM, PN, JP and LC: Conceptualization. EM: Validation, Writing—original draft, Writing—review & editing, Supervision. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

The study protocol was approved by the Ethics Committee for Health of Centro Hospitalar Universitário de São João, reference No: CE 200/2020, and complied with the principles of the Helsinki Declaration.

Consent to participate

Informed consent to participate in the study was obtained from all participants.

Consent to publication

Not applicable.

Availability of data and materials

The raw data supporting the conclusions of this manuscript will be made available by the authors, without undue reservation, to any qualified researcher.

Funding

This study is supported by a research grant from Pfizer Grant [59852013]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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