Data extraction

Author(s)YearTitleStudy designFocusSample (n)Main results
Hasler et al. [17]2005Asthma and panic in young adults: a 20-year prospective community studyProspective community studyShed light on the dynamic interaction between asthma and panic, and uncover potential mechanisms underlying their comorbidity591Asthma predicted panic, whereas panic did not predict subsequent asthma activity. Smoking, early childhood anxiety, and a family history of allergies were important confounders of the asthma-panic association
Ross et al. [18]2005Cognitive-behavioral treatment combined with asthma education for adults with asthma and coexisting panic disorderRandomized controlled trial (RCT)Tested the efficacy of cognitive-behavioral therapy (CBT) treatment combined with an asthma education (AE) program for adults with asthma suffering from coexisting PD48CBT-AE program is capable of producing substantial and durable anti-panic and antianxiety treatment effects and led to substantial but non-sustained improvement in morning peak-flow expiratory rate and asthma-related quality of life
Lehrer et al. [19]2008Psychological treatment of comorbid asthma and panic disorder: a pilot studyPilot studyEvaluate two protocols for treating adults with comorbid asthma and PD, which include elements of Barlow’s panic control therapy and several AE programs10Significant decreases in panic symptoms, clinically significant decreases in asthma symptoms, improvement in asthma quality of life, and maintenance of clinical stability in asthma. Albuterol use decreased significantly in the 14-session protocol and at a borderline level in the 8-session protocol, while the pulmonary function was maintained
Parry et al. [20]2012Cognitive behavioural intervention for adults with anxiety complications of asthma: prospective randomised trialProspective randomized trialVerify if there is a reduction in asthma-specific fear after the cognitive-behavioral intervention compared with routine treatment94Significantly greater reduction in asthma-specific fear for people in the CBT group compared with controls. At 6 months after treatment the reduction in asthma-specific fear in the CBT group was increased and the difference between the treatment and control group was statistically significant
Bonnert et al. [21]2021Targeting excessive avoidance behavior to reduce anxiety related to asthma: a feasibility study of an exposure-based treatment delivered onlineA feasibility study of an exposure-based treatment delivered onlineAssess the feasibility and potential efficacy of the online CBT30CBT for avoidance behavior is a viable treatment for anxiety-related to asthma. CBT targeting avoidance behavior is effective in reducing catastrophizing about asthma (CAS). Additionally, all secondary outcomes, such as asthma control, avoidance behavior, fear of asthma symptoms, and quality of life, improve significantly with moderate to large effect sizes
Freire et al. [22]2013The panic disorder respiratory ratio: a dimensional approach to the respiratory subtypeObservational studyDetermine whether the respiratory ratio is correlated with CO2-induced PAs and other clinical and demographic features91The respiratory ratio is correlated with CO2 sensitivity and there is a non-statistically significant trend toward a correlation with a family history of PD