From:  Metabolic dysfunction is associated with non-eosinophilic asthma phenotype: a retrospective cross-sectional study

 Eosinophilic vs. non-eosinophilic asthma patients.

VariableEosinophilic (n = 25)Non-eosinophilic (n = 65)p-value
Age (years)55 (41–64)57 (46–66)0.681
Female, n (%)17 (68.0)47 (72.3)0.796
BMI (kg/m2)26.60 (23.9–29.4)30.82 (27.1–33.5)0.023
Eosinophil (cells/µL)410 (310–700)110 (90–200)< 0.001
NLR1.74 (1.43–2.34)1.95 (1.62–2.51)0.381
Homeostatic model assessment for insulin resistance2.69 (2.11–3.29)2.96 (2.00–5.12)0.344
TyG index8.53 (8.07–9.11)8.74 (8.35–9.15)0.467
Metabolic score for insulin resistance36.91 (34.33–44.28)47.78 (41.52–53.19)0.005
CHG index5.19 (4.92–5.47)5.28 (4.99–5.62)0.602
ICS use, n (%)13 (52.0)24 (36.9)0.235

Data are presented as median (interquartile range) or n (%). Mann-Whitney U and Fisher’s exact tests were used. BMI: body mass index; CHG: cholesterol-glucose; ICS: inhaled corticosteroid; NLR: neutrophil-to-lymphocyte ratio; TyG: triglyceride-glucose.