From:  Metabolic dysfunction is associated with non-eosinophilic asthma phenotype: a retrospective cross-sectional study

 Asthma subgroup according to ICS use.

VariableICS usersNon-ICSp-value
Eosinophil (cells/µL)198 (112–320)170 (100–290)0.412
HOMA-IR2.73 (2.08–3.44)2.92 (1.96–4.88)0.287
TyG index8.39 (8.11–8.91)8.78 (8.51–9.20)0.029
Metabolic score for insulin resistance41.82 (37.20–48.73)46.12 (40.53–52.20)0.046
CHG index5.08 (4.92–5.39)5.31 (5.01–5.63)0.031

Data are presented as median (interquartile range). Mann-Whitney U test was used. ICS-containing therapies included budesonide, fluticasone, beclomethasone, and fixed-dose ICS combinations. CHG: cholesterol-glucose; HOMA-IR: homeostatic model assessment for insulin resistance; ICS: inhaled corticosteroid; TyG: triglyceride-glucose.