Exploration of Immunology

Treatment	Development of corpus luteum	Serum progesterone	Endometrium	Implantation
Deplete CD11b⁺-pan-MΦ	↓	↓	Proliferation phase	↓
Deplete CD206⁺-M2-MΦ	Normal	Normal	Proliferation phase	↓
			(M2-MΦs are essential for the differentiation of endometrial epithelial cells)

Declarations

Author contributions

SS wrote the paper, and AN consulted on the content of the paper. TS did research on Treg and consulted on the content of the paper. ST submitted materials for the paper.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

This study was supported by Japan Agency for Medical Research and Development (grant JP18gk0110018 and JP21gk0110047) and Japan Society for the Promotion of Science (KAKENHI grant JP19K09750, 20K09614, 19K18690 and 21K16764). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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