Pearson’s correlation coefficients between PASI score and the TRP-KYN pathway metabolites in PSOs
| Metabolites and ratios | Correlation coefficient |
|---|---|
| TRP | –0.28 |
| KYN | –0.01 |
| KYNA | –0.29 |
| AA | 0.38 |
| 3HK | –0.27 |
| 3HAA | –0.07 |
| KYN/TRP | 0.15 |
| KYNA/KYN | –0.33 |
| AA/KYN | 0.45 |
| 3HK/KYN | –0.22 |
| 3HAA/3HK | 0.21 |
| 3HAA/AA | –0.26 |
The authors would like to thank Mrs. Kayoko Tanaka for assisting data collection.
Seishima M and KS contributed conception and design of the study; RS and YY performed the experiments; KF and YM organized the database; Sakurai M and YY performed the statistical analysis; Seishima M wrote the first draft of the manuscript. All authors contributed to manuscript revision, read and approved the submitted version.
The authors declare that there are no conflicts of interest.
The study protocol was approved by the ethics committee of Gifu University Graduate School of Medicine (2018–1949).
The informed consent to participate in the study was obtained from all participants.
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© The Author(s) 2021.