From:  Proinflammatory cytokines in xeroderma pigmentosum (XP) and non-XP cancer patients—a pilot study

 Demographic, clinic, and histologic characteristics of the patients, demographic characteristics of the controls, the cytokines’ concentrations in the systemic circulation, and comparisons of the three groups

Individuals/DiagnosticAge(year)/GenderType/Site of the tumorIL-2 (pg/mL)IL-4 (pg/mL)IL-10 (pg/mL)TNF-α (pg/mL)
P1 (XP)31/FBCC (nose)0.78244047.17
P2 (XP)35/FBCC + SCC (cheek)4.35000
P3 (XP)17/MMultiple carcinomas (BCC + SCC) + melanoma (ear)2.3800.0127.83
P4 (XP)11/FMultiple carcinomas (BCC + SCC) face0.0808.3347
P5 (XP)39/FBCC (nasogenian furrow)00030.33
P6 (non-XP)42/MBCC (cheek)4.774.4800
P7 (non-XP)59/FSCC in situ (left side)0.76023.500
P8 (non-XP)74/MSCC (nasogenian furrow)1.3700.600
P9 (non-XP)64/MSCC (nose slot + right eye + chest)0.474.3300
P10 (non-XP)55/MBCC (cheek)1.67000
P11 (non-XP)67/FMultiple carcinomas BCC + SCC (face, cheek, and eyelids)3.5107.170
C1 (Control)57/F-0.77000
C2 (Control)39/F-000.030
C3 (Control)45/F-1.434.1700
Median concentrations of the cytokinesXP0.780.000.0030.33
Non-XP1.520.000.300.00
Control0.770.000.000.00
Comparisons of the median plasma concentrations of the cytokines in the three subgroupsXP vs non-XP (P value)0.4650.8160.6190.011
XP vs Controls (P value)> 0.9990.8450.8640.050
Non-XP vs Controls (P value)0.7960.7950.396> 0.999