Registered clinical trials of MSCs in COVID-19. In this table, a number of representable clinical trials are summarized. Data were considered as defined in the www.clinicaltrials.gov. Intravenous infusion of MSCs was performed in the listed clinical trials
NCT number
Title
Status
Phase
No of patients
MSCs origin
No of MSCs
NCT04444271
Mesenchymal Stem Cell Infusion for COVID-19 Infection
Recruiting
II
10
Frozen MSCs
2 × 106 cells/kg
NCT04713878
Mesenchymal Stem Cells Therapy in Patients With COVID-19 Pneumonia
Completed
N/A
21
Undefined
Undefined
NCT04565665
Cord Blood-Derived Mesenchymal Stem Cells for the Treatment of COVID-19 Related Acute Respiratory Distress Syndrome
Recruiting
I
70
UCB-MSCs
Undefined
NCT04416139
Mesenchymal Stem Cell for Acute Respiratory Distress Syndrome Due for COVID-19
Recruiting
II
10
Allogeneic-MSCs
1 × 106 cells/kg
NCT04252118
Mesenchymal Stem Cell Treatment for Pneumonia Patients Infected With COVID-19
Recruiting
I
20
Undefined
3 times of 3 × 107 cells
NCT04313322
Treatment of COVID-19 Patients Using Wharton’s Jelly-Mesenchymal Stem Cells
Recruiting
I
5
WJ-MSCs
Undefined
NCT04336254
Safety and Efficacy Study of Allogeneic Human Dental Pulp Mesenchymal Stem Cells to Treat Severe COVID-19 Patients
Recruiting
I/II
20
Allogeneic Dental Pulp MSCs
3 × 107 cells
NCT04611256
Mesenchymal Stem Cells in Patients Diagnosed With COVID-19
Recruiting
I
20
AT-MSCs
1 × 106 cells/kg
NCT04346368
Bone Marrow-Derived Mesenchymal Stem Cell Treatment for Severe Patients With Coronavirus Disease-19 (COVID-19)
Not Yet Recruiting
I/II
20
BM-MSCs
1 × 106 cells/kg
NCT04366271
Clinical Trial of Allogeneic Mesenchymal Cells From Umbilical Cord Tissue in Patients With COVID-19
Recruiting
II
106
Allogeneic UC-MSCs
Undefined
Declarations
Author contributions
PM wrote the initial draft of the manuscript. EM and TC revised the manuscript. CSG made the final approval for the manuscript.
Conflicts of interest
The authors declare that they have no conflicts of interest.
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