Figure 1. E-cadherin expression decreases with increasing age in premenopausal women. E-cadherin (CDH1) mRNA expression was determined by real-time reverse transcription-polymerase chain reaction (RT-PCR) for endometrial epithelial cells grown in vitro from premenopausal women (n = 14), isolated from either the proliferative or secretory phase, between the ages of 26–49 years. Expression is normalized to the expression of the housekeeping gene β-Actin. Each symbol represents an individual patient. Non-parametric Spearman correlation analysis