From:  Mitral and tricuspid annuli in hemophilia—A detailed analysis from the three-dimensional speckle-tracking echocardiographic MAGYAR-Path Study

 Baseline demographic and two-dimensional echocardiographic data of patients with hemophilia and healthy controls.

DataControls
(n = 30)
Hemophilia patients
(n = 13)
p value
Demography
    Age (years)40.4 ± 9.240.8 ± 16.30.910
    Male gender (%)30 (100)13 (100)1.000
    Hypertension (%)0 (0)4 (31)0.001
    Diabetes mellitus (%)0 (0)1 (8)0.124
    Hyperlipidaemia (%)0 (0)3 (23)0.006
2D echocardiography
    LA diameter (mm)38.5 ± 3.538.2 ± 3.40.749
    LV end-diastolic diameter (mm)48.1 ± 3.049.6 ± 2.60.119
    LV end-diastolic volume (mL)108.2 ± 18.4117.2 ± 14.70.125
    LV end-systolic diameter (mm)31.9 ± 2.131.2 ± 2.50.310
    LV end-systolic volume (mL)39.6 ± 10.338.7 ± 7.80.776
    Interventricular septum (mm)9.8 ± 1.310.1 ± 1.00.553
    LV posterior wall (mm)9.7 ± 1.69.8 ± 1.00.805
    LV ejection fraction (%)64.4 ± 2.967.1 ± 4.20.048
    E (cm/s)72.6 ± 14.871.8 ± 13.20.877
    A (cm/s)58.4 ± 17.967.2 ± 13.90.125
    E/A1.3 ± 0.21.1 ± 0.30.049

2D: two-dimensional; E and A: early and late diastolic transmitral flow velocity; LA: left atrium; LV: left ventricular.