Environmental control strategies aimed at reducing oxidative stress in asthma.
| Strategy | Main actions | Rationale/Expected benefit |
|---|---|---|
| Reduction of air pollutant exposure | Monitor daily air quality indices; limit outdoor activity on high-pollution days; use indoor HEPA filtration. | Decreases inhaled particulate and gaseous oxidants that trigger airway inflammation and oxidative stress. |
| Elimination of tobacco smoke | Maintain smoke-free homes, cars, and childcare environments. | Removes a potent source of oxidative and inflammatory airway injury; improves overall lung function. |
| Indoor allergen control | Control humidity < 50%; use mite-proof encasings; remove mold and pet dander; avoid high-VOC cleaners. | Reduces allergen-driven inflammation and secondary ROS production. |
| Ventilation and indoor air quality optimization | Ensure adequate ventilation; avoid biomass fuels, incense, and scented products. | Prevents accumulation of indoor oxidants and volatile compounds. |
| Dietary and lifestyle support | Promote antioxidant-rich diets (fruits, vegetables, nuts, olive oil) and regular physical activity. | Enhances endogenous antioxidant defenses and reduces systemic oxidative stress. |
| Public health and urban interventions | Support policies for cleaner transport, reduced industrial emissions, and green spaces around schools. | Lowers long-term population exposure to environmental oxidants and benefits community respiratory health. |
ROS: reactive oxygen species; VOC: volatile organic compounds.
The supplementary material for this article is available at: https://www.explorationpub.com/uploads/Article/file/1001420_sup_1.pdf.
MP: Conceptualization, Writing—original draft, Writing—review & editing, Validation, Visualization. MC: Conceptualization, Writing—original draft, Writing—review & editing, Validation, Visualization. ED: Conceptualization, Writing—original draft, Writing—review & editing, Validation, Visualization. AG: Writing—original draft, Writing—review & editing, Validation. ER: Writing—original draft, Writing—review & editing, Validation. GM: Writing—original draft, Writing—review & editing, Validation. GP: Writing—review & editing, Supervision, Validation, Visualization. DP: Conceptualization, Project administration, Methodology, Supervision, Writing—original draft, Writing—review & editing, Validation, Visualization. All authors read and approved the submitted version.
The authors declare that they have no conflicts of interest.
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