From:  Myofunctional therapy in sleep disorders: a systematic review

 Summary of intervention protocols across the included studies, detailing the type of therapy, specific exercises, duration, frequency, and control conditions.

StudyIntervention therapyDetailsDurationFrequencyControl therapy
Villa et al. (2015) [11]OEIsometric and isotonic exercises, nasal breathing rehabilitation, labial seal and lip tone exercises, and tongue posture exercises2 monthsThree times/day, 10–20 repetitions each timeNasal washing
Diaferia et al. (2013) [18]Myofunctional therapy + CPAP therapySoft palate, pharyngeal constrictor muscles, suprahyoid muscles, tip and root of the tongue, cheeks, and lips3 months20 min, 3 times/dayHead movements without any therapeutic function
Diaféria et al. (2017) [19]Myofunctional therapy + CPAP therapy1) Soft palate exercises
2) Tongue brushing
3) Tongue pushing and sucking
4) Tongue rotation
5) Facial exercises
3 months1) 3 min, 3 times/day
2) 5 min, 3 times/day
3) 20 min, 3 times/day
4) 10 min on each side, 3 times/day
Head movements without any therapeutic function
Erturk et al. (2020) [20]2 groups:
1) Passive myofunctional therapy with oral device
2) Active myofunctional therapy
1) IMT with a threshold IMT device
2) OE included soft palate, tongue, and facial muscle exercises
12 weeks7 days/week
5 days/week
Control group not specified
Guimarães et al. (2009) [21]OEExercises for the soft palate, tongue, and facial muscles3 monthsRepeated exercises for a total of about 20 min per dayDeep breathing and nasal washing
Villa et al. (2017) [22]OE1) Nasal breathing rehabilitation
2) Labial seal and lip tone exercises
3) Tongue posture exercises
2 monthsThree times a day, 10–20 repetitions each timeNasal washing
Ieto et al. (2015) [23]Nasal washing and OEExercises for the soft palate, tongue, and stomatognathic functions3 months8 min set of exercises (20 times), 3 times/dayDeep breathing and nasal washing
Kim et al. (2020) [24]Myofunctional therapyTongue and lips exercises12 weeksPerform 10 exercises with 10 repetitions each, and perform at least 10 sets every dayControl group that did not receive any treatment
Lin et al. (2020) [25]Daily nasal washing + myofunctional therapy and general endurance trainingRetropalatal, retroglossal, hypopharyngeal, facial, and TMJ exercises12 weeks24 sessions, daily nasal washing + upper airway muscle strengthening for 20 min, respiratory muscle strengthening for 15 min, and general endurance training for 45 minControl group that did not receive any treatment

CPAP: continuous positive airway pressure; IMT: inspiratory muscle training; OE: oropharyngeal exercises; TMJ: temporomandibular joint.