The review was conducted using the PICOS criteria.
| PICO Element | Description |
|---|---|
| Population (P) | Individuals with irreversible pulpitis in mandibular molars |
| Intervention (I) | AIT with NSAIDs, corticosteroids before treatment; truncular alveolar nerve anaesthesia |
| Comparison (C) | Truncular anaesthesia of the alveolar nerve without the use of AIT compared with different types of AIT one hour before truncular anaesthesia |
| Outcome (O) | Anaesthesia enhancement, improvement of pain control, reduction of anesthesia failure, reduction of pain intensity |
AIT: anti-inflammatory therapy; NSAIDs: non-steroidal anti-inflammatory drugs.
During the preparation of this work, the author(s) used the Adobe Firefly tool to create Figures 1 and 2. After using the tool, authors reviewed and edited the content as needed and took full responsibility for the content of the publication.
ADI: Conceptualization, Methodology, Software, Formal analysis, Resources, Data curation, Writing—original draft, Writing—review & editing, Visualization, Project administration. GM: Methodology, Formal analysis, Supervision. LPZ: Conceptualization, Validation, Formal analysis, Data curation, Writing—original draft, Supervision. AS: Conceptualization, Software, Formal analysis, Writing—original draft, Writing—review & editing, Visualization, Supervision. FED: Methodology, Validation, Formal analysis, Writing—original draft, Writing—review & editing, Visualization. FI: Conceptualization, Methodology, Validation, Formal analysis, Data curation, Writing—original draft, Writing—review & editing, Visualization, Supervision, Project administration. GMT: Conceptualization, Methodology, Supervision. MDF: Methodology, Data curation, Supervision. AP: Conceptualization, Methodology, Resources, Data curation, Writing—original draft, Writing—review & editing, Visualization, Supervision. DDV: Validation, Resources, Writing—review & editing, Project administration. AMI: Conceptualization, Methodology, Validation, Formal analysis, Resources, Data curation, Writing—original draft, Writing—review & editing, Visualization, Project administration. GD: Methodology, Software, Validation, Formal analysis, Resources, Data curation, Writing—original draft, Writing—review & editing, Visualization, Project administration. All authors have read and agreed to the published version of the manuscript.
The authors declare no conflicts of interest.
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The primary data for this systematic review were sourced online from databases listed in the methods. Referenced articles are accessible on Scopus, Web of Science, and PubMed. Additional supporting data are available from the corresponding author upon request.
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