From:  Effectiveness of fluoroquinolone de-escalation in community-acquired pneumonia: impact on hospital stay and mortality

 Comparison of patient demographics and clinical outcomes between successful and failed/inappropriate antibiotic de-escalation groups.

ParameterSuccessfully de-escalated
(n = 41)
Failed/Inappropriate de-escalated
(n = 81)
P-value
Age (years), median (IQR)74.0 (20.0)71.0 (25.0)0.659^
Gender, n (%)
    Female15 (36.6%)27 (33.3%)0.721#
    Male26 (63.4%)54 (66.7%)
ICU admission, n (%)
    Yes8 (19.5%)12 (14.8%)0.324#
    No33 (80.5%)64 (79.0%)
    Already admitted to ICU0 (0%)5 (6.2%)
Length of hospital stay (days), median (IQR)12 (8.0)18 (11.0)0.004*^
In-hospital mortality, n (%)
    Survived29 (70.7%)62 (76.5%)0.514#
    Died12 (29.3%)19 (23.5%)

*: Significant at 0.05 significance level; ^: using Mann-Whitney U test; #: using Chi-square/Fisher exact test. IQR: interquartile range.