From:  Closing gaps in blood pressure control: a look at two major approaches

 Fixed dose combination therapy advantages and challenges

AdvantagesChallenges
Decreased pill burden
Decreased co-pay/cost
Increased adherence
Decreased clinical inertia
Decreased blood pressure
Complementary mechanisms
Decreased CVD events
Availability of dose options
Availability of drug choice combinations
Access to fixed dose combinations
Cost (inconsistent coverage)
Inconsistent guideline recommendations for blood pressure goals and use
Prescriber reluctance

Fixed dose combination drugs for hypertension offer many advantages, although there are a few challenges to consider. CVD: cardiovascular disease