Table Info

Table 4.

Enrichr-KG pathways and associated gene table (European)

Pathway	Associated genes	Role in breast cancer (BC)
Cholesterol metabolism	CD36 (cluster of differentiation 36), APOB (apolipoprotein B)	Influences BC progression, aggressiveness, and drug resistance
Decreased circulating adiponectin level	CAV1 (caveolin-1), CD36, PPARG (peroxisome proliferator-activated receptor gamma)	Contribute to breast tumor development and progression
Adipocytokine signaling pathway	LEP, CD36	Influence BC cell survival, growth, invasion, and metastasis
AMP-activated protein kinase (AMPK) signaling pathway	CD36, LEP, PPARG, IGF1 (insulin-like growth factor 1)	Functions as a tumor suppressor
Increased circulating triglyceride level	CAV1, LEP, PPARG, APOB, CD36	Influence cancer cell growth and survival
Abnormal glucose homeostasis	CAV1, LEP, IGF1, CD36, PPARG	Increases the proliferation of BC cells

Supplementary materials

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Declarations

Author contributions

PM: Project administration, Conceptualization, Validation, Supervision, Writing—review & editing. SS: Conceptualization, Validation, Data curation, Methodology, Writing—review & editing. SR: Data curation, Methodology, Writing—original draft.

Conflicts of interest

The author declares that there are no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

All datasets (generated/analyzed) for this study are included in the manuscript and the supplementary files.

Funding

Not applicable.

Copyright

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