Table Info

Table 3.

Enrichr-KG pathways and associated gene table (Asian)

Pathway	Associated genes	Role in breast cancer (BC)
Cholesterol metabolism	CD36 (cluster of differentiation 36), LEP (leptin)	Influences BC progression, aggressiveness, and drug resistance
Impaired adaptive thermogenesis	CAV1 (caveolin-1), LEP, CD36, PLIN1 (perilipin 1)	Promote cancer cell survival and growth
Adipocytokine signaling pathway	LEP, CD36	Influence BC cell survival, growth, invasion, and metastasis
Positive regulation of mitogen-activated protein kinase (MAPK) cascade	LEP, CD36	Key in cell proliferation and death
AMP-activated protein kinase (AMPK) signaling pathway	CD36, LEP	Functions as a tumor suppressor
Increased oxygen consumption	CAV1, LEP, PLIN1	Increase tumor proliferation
Abnormal glucose homeostasis	CAV1, LEP, PLIN1, CD36	Increases the proliferation of BC cells

Supplementary materials

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Declarations

Author contributions

PM: Project administration, Conceptualization, Validation, Supervision, Writing—review & editing. SS: Conceptualization, Validation, Data curation, Methodology, Writing—review & editing. SR: Data curation, Methodology, Writing—original draft.

Conflicts of interest

The author declares that there are no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

All datasets (generated/analyzed) for this study are included in the manuscript and the supplementary files.

Funding

Not applicable.

Copyright

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