Comparing means of systolic blood pressure (mmHg) in the study groups (before, at the end of the intervention, and one month after the end of the intervention) (results of repeated measures ANOVA analysis)
Time
Group effect
Time effect
Group and time interaction
Before intervention (Time 1)
0.923
0.007
< 0.0001
End of the intervention (Time 2)
0.836
0.279
0.011
One month after the end of the intervention (Time 3)
MN: Conceptualization, Supervision, Validation, Writing—review & editing. TS: Conceptualization, Supervision, Data curation, Methodology, Formal analysis, Writing—original draft. HS: Supervision, Validation, Writing—review & editing, Formal analysis. RG and HBT: Supervision, Validation, Writing—review & editing. All authors read and approved the submitted version.
Conflicts of interest
The authors declare that they have no conflicts of interest.
Ethical approval
The research project, which obtained permission from the research ethics committee of Birjand University of Medical Sciences, was approved with the code of IR.BUMS.REC.1400.443 and was registered in the Iranian Registry of Clinical Trials (IRCT) at https://irct.behdasht.gov.ir/ with the code IRCT20221223056899N1.
Consent to participate
Informed consent was obtained from the participants before the implementation of the study, and during the implementation of the study, the patients could not continue their cooperation with the project if they were not willing to participate anymore.
Consent to publication
Not applicable.
Availability of data and materials
The data are available on request from the corresponding author.
Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.
References
Zhang F, Bai Y, Zhao X, Huang L, Zhang Y, Zhang H. The impact of exercise intervention for patients undergoing hemodialysis on fatigue and quality of life: A protocol for systematic review and meta-analysis.Medicine (Baltimore). 2020;99:e21394. [DOI] [PubMed] [PMC]
Alosaimi FD, Alshahrani SM, Aladhayani MH, Alwethenani ZK, Alsahil MJ, Fadhul HA. Psychosocial predictors of quality of life among chronic hemodialysis patients.Saudi Med J. 2020;41:990–8. [DOI] [PubMed] [PMC]
Rehman IU, Wu DB, Ahmed R, Khan NA, Rahman AU, Munib S, et al. A randomized controlled trial for effectiveness of zolpidem versus acupressure on sleep in hemodialysis patients having chronic kidney disease-associated pruritus.Medicine (Baltimore). 2018;97:e10764. [DOI] [PubMed] [PMC]
Koushan M, Rakhshani MH, Mohsenpour M, Heshmatifar N. The effect of Benson Relaxation Response on Hemodialysis Patients’ Fatigue.Q J Sabzevar Univ Med Sci. 2014;20:757–65. Farsi.
Mastnardo D, Lewis JM, Hall K, Sullivan CM, Cain K, Theurer J, et al. Intradialytic Massage for Leg Cramps Among Hemodialysis Patients: a Pilot Randomized Controlled Trial.Int J Ther Massage Bodywork. 2016;9:3–8. [DOI] [PubMed] [PMC]
Hydarinia Naieni Z, Nobahar M, Ghorbani R. The relationship between sleep quality in patients’ undergoing hemodialysis at different therapeutic’ shifts.Koomesh J. 2017;18:42–50. Farsi.
Dehghani A, Alishavandi S, Nourimajalan N, Fallahzadeh H, Rahmanian V. Prevalence of chronic kidney diseases and its determinants among Iranian adults: results of the first phase of Shahedieh cohort study.BMC Nephrol. 2022;23:203. [DOI] [PubMed] [PMC]
Palmer SC, Natale P, Ruospo M, Saglimbene VM, Rabindranath KS, Craig JC, et al. Antidepressants for treating depression in adults with end-stage kidney disease treated with dialysis.Cochrane Database Syst Rev. 2016;2016:CD004541. [DOI] [PubMed] [PMC]
Elali ES, Mahdavi A, Jannati Y, Cherati JY, Setareh J. Effect of Benson Relaxation Response on Stress Among in Hemodialysis Patients.J Mazandaran Univ Med Sci. 2012;22:61–8. Farsi.
Rahdar Z, Haghighi MJ, Mansouri A, Siasary A, Alahyari J, Jahantigh F. Probing the Relationship Between Treatment Regimen Compliance and the Quality of Life in Hemodialysis Patients: A Descriptive-Analytic Study.Med Surg Nurs J. 2019;8:e95599. [DOI]
Bouya S, Allahyari J, Hesaraki M, Koochakzai M, Maleknejad A. The importance of health literacy in patients with chronic kidney disease: A literature review.Prensa Med Argent. 2018;104:6.
Vendemia F, D’Amico G. Antihypertensive Therapy in Dialysed Patients.Contrib Nephrol. 1988;61:161–70. [DOI] [PubMed]
Eimani E, Moshtaqeshgh Z, Ali Hoseini T, Alavi Majd H, AbedSaeidi J. The Effect of Foot Massage on Physiological Indicators of Female Patients with CVA Admitted in the ICU.J Shahid Sadoughi Univ Med Sci. 2009;17:209–15. Farsi.
Abadi F, Abadi F, Fereidouni Z, Amirkhani M, Karimi S, Najafi Kalyani M. Effect of Acupressure on Preoperative Cesarean Section Anxiety.J Acupunct Meridian Stud. 2018;11:361–6. [DOI] [PubMed]
Schouten RW, Nadort E, Harmse V, Honig A, van Ballegooijen W, Broekman BFP, et al. Symptom dimensions of anxiety and their association with mortality, hospitalization and quality of life in dialysis patients.J Psychosom Res. 2020;133:109995. [DOI] [PubMed]
Farhad L, Brazparandjani S, Latifi SM, Chahkhoei M, Khalili A, Paymard A, et al. The Effect of Collaborative Care model on the Fatigue in Patients Undergoing Maintenance Hemodialysis: A Randomized Clinical Trial.Qom Univ Med Sci J. 2016;10:71–9. Farsi.
Asadi N, Royani Z, Abbaszadeh A. A study of some fatigue-related factors based on unpleasant symptoms theory in Kerman-resident hemodialysis patients.Modern Care J. 2014;11:119–26.
Tavakoli M, Roshandel M, Zareiyan A, Dabagh Moghadam A. Evaluation of Fatigue in Hemodialysis Patients in AJA Selected Hospitals.Military Caring Sci. 2016;2:197–205. Farsi.
Mendes FCO, Santos KVGD, Dantas JKDS, Araújo SCMd, Teixeira FC, Leal KCDS, et al. Non-pharmacological strategies to reduce stress and anxiety in endovascular procedures: A scoping review.Nurs Open. 2024;11:e2105. [DOI] [PubMed] [PMC]
Williams A, Ishimine P. Non-pharmacologic Management of Pain and Anxiety in the Pediatric Patient.Curr Emerg Hosp Me R. 2016;4:26–31.
Moazami Goudarzi Y, Ghadirian F, Vahedian A, Pishgoo A. The Effectof Benson Relaxation on the Anxiety of Patients under Radial Angiography: A Randomized Clinical Trial.J Crit Care Nurs. 2018;11:1–6. Farsi.
Tayebi A, Kasra Dehkordi A, Ebadi A, Sahraei H, Einollahi B. The Effect of Aromatherapy with Lavender Essential Oil on Depression, Anxiety and Stress in Hemodialysis Patients: A Clinical Trial.Evid Based Care J. 2015;5:65–74. [DOI]
Dehghanmehr S, Sargazi GH, Biabani A, Nooraein S, Allahyari J. Comparing the Effect of Acupressure and Foot Reflexology on Anxiety and Depression in Hemodialysis Patients: A Clinical Trial.Med Surg Nurs J. 2019;8:e100386. [DOI]
Kao C, Chen C, Lin W, Chiao Y, Hsieh C. Effect of Auricular Acupressure on Peri- and Early Postmenopausal Women with Anxiety: A Double-Blinded, Randomized, and Controlled Pilot Study.Evid Based Complement Alternat Med. 2012;2012:567639. [DOI] [PubMed] [PMC]
Cho Y, Joo J, Kim S, Sok S. Effects of Meridian Acupressure on Stress, Fatigue, Anxiety, and Self-Efficacy of Shiftwork Nurses in South Korea.Int J Environ Res Public Health. 2021;18:4199. [DOI] [PubMed] [PMC]
Khanghah AG, Rizi MS, Nabi BN, Adib M, Leili EKN. Effects of Acupressure on Fatigue in Patients with Cancer Who Underwent Chemotherapy.J Acupunct Meridian Stud. 2019;12:103–10. [DOI] [PubMed]
Tse M, Au J. The effects of acupressure in older adults with chronic knee pain: Depression, pain, activities of daily living and mobility.J Pain Manag. 2010;3:339–410.
Song Y, Hu R, Diao Y, Chen L, Jiang X. Effects of Exercise Training on Restless Legs Syndrome, Depression, Sleep Quality, and Fatigue Among Hemodialysis Patients: A Systematic Review and Meta-analysis.J Pain Symptom Manage. 2018;55:1184–95. [DOI] [PubMed]
Behdani F, Sargolzaei M, Ghorbani E, editors. Study of the relationship between lifestyle and prevalence of depression and anxiety in the students of sabzevar universities. 2000.
Salari P, Alavian F, Habibi Rad A, Tara F. The Relationship between Stress, Anxiety and Pain with Salivary Cortisol Levels in First Stage of Labor in Primiparous Women.Iran J Obstet Gyne Infertil. 2013;16:14–21.
Sharif Nia H, Pahlevan Sharif S, Yaghoobzadeh A, Yeoh KK, Goudarzian AH, Soleimani MA, et al. Effect of acupressure on pain in Iranian leukemia patients: A randomized controlled trial study.Int J Nurs Pract. 2017;23:e12513. [DOI] [PubMed]
Siasari A, Zamani Afshar M, Sargolzaie F, Saberi N, Dehghanmehr S. The Effect of Acupressure at P6 Point on Anxiety and Depression in Hemodialysis Patients.Compl Med J. 2020;10:174–83. [DOI]
Moradi M, Azizi H, Saffari SE, Koushan M. The effect of Acupressure on Anxiety in Patients with Hemodialysis.J Sabzevar Univ Med Sci. 2015;22:765–2. Farsi.
Mousavi S, Mirzaei M, Soltani P. The Effects of Acupressure on Anxiety Nursing, Midwifery and Operating Room Students.J Guilan Univ Med Sci. 2009;18:82–9.
Kafaei Atrian M, Sameie A, Sarvieh M, Mirbagher Ajorpaz N, Asghari Jafarabadi M. Comparison of the effect of acupressure at spleen 6 and liver 3 points on the anxiety level of patients with primary dysmenorrhea—Blind randomized controlled clinical trial.J Kermanshah Univ Med Sci. 2014;18:256–64. Farsi.
Hmwe NTT, Subramanian P, Tan LP, Chong WK. The effects of acupressure on depression, anxiety and stress in patients with hemodialysis: A randomized controlled trial.Int J Nurs Stud. 2015;52:509–18. [DOI] [PubMed]
Li J, Zhang K, Zhao T, Huang W, Hou R, Wang S, et al. Acupressure for depression: A systematic review and meta-analysis.Asian J Psychiatr. 2024;92:103884. [DOI] [PubMed]
Amini Rarani S, Rajai N, Sharififar S. Effects of acupressure at the P6 and LI4 points on the anxiety level of soldiers in the Iranian military.BMJ Mil Health. 2021;167:177–81. [DOI] [PubMed]
Eğlence R, Karataş N, Taşci S. The effect of acupressure on the level of fatigue in hemodialysis patients.Altern Ther Health Med. 2013;19:23–31. [PubMed]
Kalani L, Aghababaeian H, Majidipour N, Alasvand M, Bahrami H, Fakhri S, et al. The effects of acupressure on severity of depression in hemodialysis patients: a randomized controlled Trial.J Adv Pharm Educ Res. 2019;9:69–72.
Suandika M, Chen S, Fang J, Yang S, Tsai Y, Weng L, et al. Effect of Acupressure on Fatigue in Hemodialysis Patients: A Single-Blinded Randomized Controlled Trial.J Integr Complement Med. 2023;29:111–8. [DOI] [PubMed]
Jones DJW, Butler LT, Harris JP, Vaux EC. Latent learning in End Stage Renal Disease (ESRD).Physiol Behav. 2015;142:42–7. [DOI] [PubMed]
Liu C, Yang J, Li H, He P, Deng Y, Dong A, et al. Acupressure for sleep disorders, fatigue, depression and pruritus in hemodialysis patients: A systematic review and meta-analysis.Research Square [Preprint]. 2023 [cited 2023 Mar 6]. Available from: https://www.researchsquare.com/article/rs-2579123/v1 [DOI]
Hadadian F, Sohrabi N, Farokhpayam M, Farokhpayam H, Towhidi F, Fayazi S, et al. The Effects of Transcutaneous Electrical Acupoint Stimulation (TEAS) on Fatigue in Haemodialysis Patients.J Clin Diagn Res. 2016;10:YC01–4. [DOI] [PubMed] [PMC]
Valiee S, Bassampour SS, Nasrabadi AN, Pouresmaeil Z, Mehran A. Effect of Acupressure on Preoperative Anxiety: A Clinical Trial.J Perianesth Nurs. 2012;27:259–66. [DOI] [PubMed]
Bassampour SH, Nikbakht Nasrabadi A, Mehran A, Poresmaeil Z, Valiee S. Effect of Acupressure on Patients’ Anxiety and Vital Sign before Abdominal Surgeries.J Hayat. 2008;14:23–34.
Barker R, Kober A, Hoerauf K, Latzke D, Adel S, Kain ZN, et al. Out-of-hospital Auricular Acupressure in Elder Patients with Hip Fracture: A Randomized Double-Blinded Trial.Acad Emerg Med. 2006;13:19–23. [DOI] [PubMed]
Chen H, Chang F, Hsu C. Effect of acupressure on nausea, vomiting, anxiety and pain among post-cesarean section women in Taiwan.Kaohsiung J Med Sci. 2005;21:341–50. [DOI] [PubMed]
Vasokolaei ZR, Rejeh N, Heravi-Karimi M, Tadrisi SD, Poshtchaman Z, Zamani F. Effect of Acupressure on Anxiety and Hemodynamic Parameters in Female Patients with Acute Coronary Syndrome Hospitalized in Cardiac Care Unit: A Randomized Placebo Controlled Clinical Trial.J Nurs Educ. 2019;7:15–22.
Hamidzadeh A, Tavakol Z, Maleki M, Kolahdozan S, Khosravi A, Kiani M, et al. Effect of acupressure at the BL67 spot on the spontaneous rotation of fetus with breech presentation: A randomized controlled trial.Explore (NY). 2022;18:567–72. Farsi. [DOI] [PubMed]
Rogers P. Serious complications of acupuncture or acupuncture abuses?Am J Acupuncture. 2012;9:347–51.
