From:  The effect of acupressure on anxiety, fatigue, and blood pressure in hemodialysis patients: a randomized controlled trial study

 Comparison of the average fatigue among the study groups (before, at the end of the intervention, and one month after the end of the intervention)

TimeIntervention (Mean ± SD)Sham (Mean ± SD)Control (Mean ± SD)Test result*
Test statisticsp-value
Before intervention (Time 1)141.06 ± 39.54138.59 ± 33.25151.44 ± 24.791.4200.247
End of the intervention (Time 2)124.29 ± 38.36135.16 ± 38.74149.67 ± 23.164.7410.011
One month after the end of the intervention (Time 3)131.94 ± 37.04137.28 ± 35.03150.09 ± 23.042.8380.063
p-value< 0.00010.0310.459--
Score differences during intervention timesTime 2 – Time 1–16.76 ± 7.76–3.44 ± 7.24–1.76 ± 10.2931.140< 0.0001
Time 3 – Time 1–9.12 ± 6.23–1.31 ± 3.29–1.35 ± 10.5912.519< 0.0001
Results of variance analysis of one-way repeated measuresGroup and time interaction---12.519< 0.0001
Group effect---2.7290.070
Time effect---28.381< 0.0001

SD: standard deviation; -: not applicable; * one-way repeated measures ANOVA