Table Info

Table 3.

Comparison of clinical course between the groups

Variables	Group I (N = 24)	Group II (N = 79)	P-value^*
Duration of respirator use (days)	4.17 ± 1.97	0.13 ± 0.11	< 0.001
Duration of central venous catheter use (days)	19.33 ± 10.71	14.65 ± 6.90	0.003
Duration of urethra catheter use (days)	9.38 ± 4.61	4.15 ± 2.54	< 0.001
Duration of antibiotic use (days)	15.13 ± 8.29	9.30 ± 4.31	< 0.001
Post operation stay (days)	24.63 ± 15.50	16.97 ± 8.76	< 0.001
ICU stay (days)	8.29 ± 3.30	2.70 ± 1.75	< 0.001
Hospital stay (days)	34.25 ± 17.03	25.50 ± 9.29	< 0.001

^* Compared with the analysis of variance for interval data or chi-square test for categorical data

Declarations

Author contributions

ZF and Hao Y: Conceptualization, Data curation, Formal analysis, Writing—original draft, Writing—review & editing. YL, DX, BS, Huguang Y, and CX: Data curation, Formal analysis. FX: Writing—review & editing. LL: Conceptualization, Writing—review & editing. All authors reviewed and approved the final manuscript.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

The ethics committee of Chongqing University Cancer Hospital granted ethical approval for this study (ethical approval number: CZLS2020040-A), which complied with the Declaration of Helsinki.

Consent to participate

Informed consent to participate in the study was obtained from all participants.

Consent to publication

Not applicable.

Availability of data and materials

All datasets for this study are included in the manuscript.

Funding

This work was supported by Chongqing Science and Health Joint Medical Research Project No. [2023MSXM039]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

References

Matz M, Valkov M, Šekerija M, Luttman S, Caldarella A, Coleman MP, et al. Worldwide trends in esophageal cancer survival, by sub-site, morphology, and sex: an analysis of 696,974 adults diagnosed in 60 countries during 2000-2014 (CONCORD-3). Cancer Commun (Lond). 2023;43:963–80. [DOI] [PubMed] [PMC]

Abou Chaar MK, Godin A, Harmsen WS, Wzientek C, Saddoughi SA, Hallemeier CL, et al. Determinants of long-term survival decades after esophagectomy for esophageal cancer. Ann Thorac Surg. 2023;116:1036–44. [DOI] [PubMed]

Gu YM, Zhang HL, Yang YS, Yuan Y, Hu Y, Che GW, et al. Short- and long-term outcomes of totally versus hybrid minimally invasive Ivor Lewis oesophagectomy for oesophageal cancer: a propensity score-matched analysis. Front Oncol. 2022;12:849250. [DOI] [PubMed] [PMC]

Zhang Y, Dong D, Cao Y, Huang M, Li J, Zhang J, et al. Robotic versus conventional minimally invasive esophagectomy for esophageal cancer: a meta-analysis. Ann Surg. 2023;278:39–50. [DOI] [PubMed]

Atkins BZ, Shah AS, Hutcheson KA, Mangum JH, Pappas TN, Harpole DH Jr, et al. Reducing hospital morbidity and mortality following esophagectomy. Ann Thorac Surg. 2004;78:1170–6. [DOI] [PubMed]

Ferguson MK, Durkin AE. Preoperative prediction of the risk of pulmonary complications after esophagectomy for cancer. J Thorac Cardiovasc Surg. 2002;123:661–9. [DOI] [PubMed]

Nilsson K, Klevebro F, Rouvelas I, Lindblad M, Szabo E, Halldestam I, et al. Surgical morbidity and mortality from the multicenter randomized controlled NeoRes II trial: standard versus prolonged time to surgery after neoadjuvant chemoradiotherapy for esophageal cancer. Ann Surg. 2020;272:684–9. [DOI] [PubMed]

Duff AM, Lambe G, Donlon NE, Donohoe CL, Brady AM, Reynolds JV. Interventions targeting postoperative pulmonary complications (PPCs) in patients undergoing esophageal cancer surgery: a systematic review of randomized clinical trials and narrative discussion. Dis Esophagus. 2022;35:doac017. [DOI] [PubMed]

Oh TK, Song IA. Risk factors and outcomes of fatal respiratory events after esophageal cancer surgery from 2011 through 2018: a nationwide cohort study in South Korea. Esophagus. 2022;19:401–9. [DOI] [PubMed]

10.

Uchihara T, Yoshida N, Baba Y, Yagi T, Toihata T, Oda E, et al. Risk factors for pulmonary morbidities after minimally invasive esophagectomy for esophageal cancer. Surg Endosc. 2018;32:2852–8. [DOI] [PubMed]

11.

Bailey SH, Bull DA, Harpole DH, Rentz JJ, Neumayer LA, Pappas TN, et al. Outcomes after esophagectomy: a ten-year prospective cohort. Ann Thorac Surg. 2003;75:217–22. [DOI] [PubMed]

12.

Law S, Wong KH, Kwok KF, Chu KM, Wong J. Predictive factors for postoperative pulmonary complications and mortality after esophagectomy for cancer. Ann Surg. 2004;240:791–800. [DOI] [PubMed] [PMC]

13.

Fang W, Kato H, Tachimori Y, Igaki H, Sato H, Daiko H. Analysis of pulmonary complications after three-field lymph node dissection for esophageal cancer. Ann Thorac Surg. 2003;76:903–8. [DOI] [PubMed]

14.

Blackmon SH, Correa AM, Wynn B, Hofstetter WL, Martin LW, Mehran RJ, et al. Propensity-matched analysis of three techniques for intrathoracic esophagogastric anastomosis. Ann Thorac Surg. 2007;83:1805–13. [DOI] [PubMed]

15.

Hirano Y, Konishi T, Kaneko H, Itoh H, Matsuda S, Kawakubo H, et al. Impact of prophylactic corticosteroid use on in-hospital mortality and respiratory failure after esophagectomy for esophageal cancer: nationwide inpatient data study in Japan. Ann Surg. 2023;277:e1247–53. [DOI] [PubMed]

16.

Panda N, Shagabayeva L, Comrie CE, Phan N, Moonsamy P, Jeffrey Yang CF, et al. Drivers of cost associated with minimally invasive esophagectomy. Ann Thorac Surg. 2022;113:264–70. [DOI] [PubMed]

17.

Park SY, Lee HS, Jang HJ, Joo J, Zo JI. Efficacy of intraoperative, single-bolus corticosteroid administration to prevent postoperative acute respiratory failure after oesophageal cancer surgery. Interact Cardiovasc Thorac Surg. 2012;15:639–43. [DOI] [PubMed] [PMC]

18.

Morita M, Yoshida R, Ikeda K, Egashira A, Oki E, Sadanaga N, et al. Acute lung injury following an esophagectomy for esophageal cancer, with special reference to the clinical factors and cytokine levels of peripheral blood and pleural drainage fluid. Dis Esophagus. 2008;21:30–6. [DOI] [PubMed]

19.

Dong J, Wang GD, Wang HZ. Clinical analysis of patients with respiratory failure after esophageal cancer operation. Transl Cancer Res. 2021;10:5238–45. [DOI] [PubMed] [PMC]

20.

Ohi M, Toiyama Y, Omura Y, Ichikawa T, Yasuda H, Okugawa Y, et al. Risk factors and measures of pulmonary complications after thoracoscopic esophagectomy for esophageal cancer. Surg Today. 2019;49:176–86. [DOI] [PubMed]

21.

MacIntyre NR. Current issues in mechanical ventilation for respiratory failure. Chest. 2005;128:561S–7S. [DOI] [PubMed]

22.

Cobelens PM, van Putte BP, Kavelaars A, Heijnen CJ, Kesecioglu J. Inflammatory consequences of lung ischemia-reperfusion injury and low-pressure ventilation. J Surg Res. 2009;153:295–301. [DOI] [PubMed]

23.

Deana C, Vetrugno L, Bignami E, Bassi F. Peri-operative approach to esophagectomy: a narrative review from the anesthesiological standpoint. J Thorac Dis. 2021;13:6037–51. [DOI] [PubMed] [PMC]

24.

Fujishima S. Guideline-based management of acute respiratory failure and acute respiratory distress syndrome. J Intensive Care. 2023;11:10. [DOI] [PubMed] [PMC]

25.

Whooley BP, Law S, Murthy SC, Alexandrou A, Wong J. Analysis of reduced death and complication rates after esophageal resection. Ann Surg. 2001;233:338–44. [DOI] [PubMed] [PMC]

26.

Deana C, Vetrugno L, Stefani F, Basso A, Matellon C, Barbariol F, et al. Postoperative complications after minimally invasive esophagectomy in the prone position: any anesthesia-related factor. Tumori. 2021;107:525–35. [DOI] [PubMed]

27.

Sun Y, Zhu Y. Impairment of lung function increases the risk of postoperative respiratory failure for esophageal carcinoma: a systematic review and meta-analysis. J Healthc Eng. 2021;2021:5327682. [DOI] [PubMed] [PMC]

28.

Shinozaki H, Matsuoka T, Ozawa S. Pharmacological treatment to reduce pulmonary morbidity after esophagectomy. Ann Gastroenterol Surg. 2021;5:614–22. [DOI] [PubMed] [PMC]

29.

Reynolds JV, Ravi N, Hollywood D, Kennedy MJ, Rowley S, Ryan A, et al. Neoadjuvant chemoradiation may increase the risk of respiratory complications and sepsis after transthoracic esophagectomy. J Thorac Cardiovasc Surg. 2006;132:549–55. [DOI] [PubMed]

30.

Jiao WJ, Wang TY, Gong M, Pan H, Liu YB, Liu ZH. Pulmonary complications in patients with chronic obstructive pulmonary disease following transthoracic esophagectomy. World J Gastroenterol. 2006;12:2505–9. [DOI] [PubMed] [PMC]

31.

Atkins BZ, D’Amico TA. Respiratory complications after esophagectomy. Thorac Surg Clin. 2006;16:35–48. [DOI] [PubMed]

32.

Grotenhuis BA, Wijnhoven BP, Grüne F, van Bommel J, Tilanus HW, van Lanschot JJ. Preoperative risk assessment and prevention of complications in patients with esophageal cancer. J Surg Oncol. 2010;101:270–8. [DOI] [PubMed]

33.

Ferguson MK, Celauro AD, Prachand V. Prediction of major pulmonary complications after esophagectomy. Ann Thorac Surg. 2011;91:1494–501. [DOI] [PubMed]

34.

Bakhos CT, Fabian T, Oyasiji TO, Gautam S, Gangadharan SP, Kent MS, et al. Impact of the surgical technique on pulmonary morbidity after esophagectomy. Ann Thorac Surg. 2012;93:221–7. [DOI] [PubMed]

35.

Nakamura M, Iwahashi M, Nakamori M, Ishida K, Naka T, Iida T, et al. An analysis of the factors contributing to a reduction in the incidence of pulmonary complications following an esophagectomy for esophageal cancer. Langenbecks Arch Surg. 2008;393:127–33. [DOI] [PubMed]

36.

Yoshida N, Watanabe M, Baba Y, Iwagami S, Ishimoto T, Iwatsuki M, et al. Risk factors for pulmonary complications after esophagectomy for esophageal cancer. Surg Today. 2014;44:526–32. [DOI] [PubMed]

37.

Kuwabara S, Kobayashi K, Sudo N. Outcomes of elderly patients following thoracoscopic esophagectomy for esophageal cancer. Langenbecks Arch Surg. 2023;408:56. [DOI] [PubMed]

38.

Takahashi T, Hashimoto H, Noro T, Hino Y, Hirashima T, Kuroiwa K, et al. Risk factors of operative death and prognosis following operations for esophageal cancer in the elderly. Nihon Ronen Igakkai Zasshi. 1995;32:781–5. Japanese. [DOI] [PubMed]

39.

Molena D, Mungo B, Stem M, Lidor AO. Incidence and risk factors for respiratory complications in patients undergoing esophagectomy for malignancy: a NSQIP analysis. Semin Thorac Cardiovasc Surg. 2014;26:287–94. [DOI] [PubMed]

40.

Mao YS, Zhang DC, He J, Zhang RG, Cheng GY, Sun KL, et al. Postoperative respiratory failure in patients with cancer of esophagus and gastric cardia. Zhonghua Zhong Liu Za Zhi. 2005;27:753–6. Chinese. [PubMed]

41.

Arméstar F, Mesalles E, Font A, Arellano A, Roca J, Klamburg J, et al. Serious postoperative complications after esophagectomy for esophageal carcinoma: analysis of risk factors. Med Intensiva. 2009;33:224–32. Spanish. [DOI] [PubMed]

42.

Mayr VD, Dünser MW, Greil V, Jochberger S, Luckner G, Ulmer H, et al. Causes of death and determinants of outcome in critically ill patients. Crit Care. 2006;10:R154. [DOI] [PubMed] [PMC]

43.

Canet J, Gallart L, Gomar C, Paluzie G, Vallès J, Castillo J, et al.; ARISCAT Group. Prediction of postoperative pulmonary complications in a population-based surgical cohort. Anesthesiology. 2010;113:1338–50. [DOI] [PubMed]

44.

Melsen WG, Rovers MM, Groenwold RH, Bergmans DC, Camus C, Bauer TT, et al. Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies. Lancet Infect Dis. 2013;13:665–71. [DOI] [PubMed]