Table Info

Table 2.

Biochemical assessment of study participants

Parameters	Group I (SAM with complications) (mean ± SD)	Group II (SAM without complications) (mean ± SD)	P value
Hb (g/dL)	8.86 ± 2.21	10.00 ± 1.83	0.003^**
TLC (cells/mm³)	15,374 ± 7,455	13,558 ± 3,602	0.723
Platelet count (million cells/mm³)	0.33 ± 0.15	0.35 ± 0.12	0.393
Red blood cell (million cells/mm³)	4.26 ± 0.87	4.22 ± 0.43	0.753
Mean platelet volume (fL)	8.99 ± 2.39	8.86 ± 1.22	0.710
Urea (mg/dL)	29.60 ± 13.90	28.30 ± 5.08	0.513
Creatinine (mg/dL)	0.81 ± 0.23	0.82 ± 0.11	0.683
Bilirubin total (mg/dL)	0.69 ± 0.69	0.49 ± 0.12	0.055
Bilirubin direct (mg/dL)	0.47 ± 0.57	0.22 ± 0.08	< 0.001^**
Bilirubin indirect (mg/dL)	0.34 ± 0.27	0.27 ± 0.08	0.064
Protein (mg/dL)	6.72 ± 0.80	7.18 ± 0.68	0.002^**
Albumin (mg/dL)	4.15 ± 0.52	4.63 ± 0.52	0.001^**
SGOT (IU/L)	67.3 ± 87.4	45.7 ± 14.3	0.031**
SGPT (IU/L)	49.6 ± 53.4	31.2 ± 14.4	0.009**

Hb: hemoglobin; TLC: total leukocytes count; SGPT: serum glutamic pyruvic transaminase; SGOT: serum glutamic oxaloacetic transaminase; SAM: severe acute malnutrition; ^** P value < 0.05 was considered significant

Declarations

Acknowledgments

We thank the whole team at the study’s participating facilities for their support in patient recruiting as well as their logistical and administrative assistance. In addition, we want to thank everyone who agreed to take part in the study. We extend our special thanks to Tanu Midha of G.S.V.M. Medical College, Kanpur, for her diligent efforts and professional assistance throughout the statistical analysis of the article. We acknowledge Indian Council of Medical Research (ICMR) for enabling this study.

Author contributions

MM: Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Visualization, Writing—original draft, Writing—review & editing. PT: Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing—original draft, Writing—review & editing. PS: Methodology. YKR: Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing—review & editing. DDS: Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing—Review & Editing.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Ethical approval has been obtained from the Institutional Ethics Committee (IEC), G.S.V.M. Medical College, Kanpur. No. EC/139/August/2021, dated August 25, 2021.

Consent to participate

The informed consent of all participants was obtained before their involvement in this study.

Consent to publication

Not applicable.

Availability of data and materials

The raw data supporting the conclusions of this manuscript will be made available by the authors, without undue reservation, to any qualified researcher.

Funding

The authors acknowledge the Indian Council of Medical Research Senior Research Fellowship grant [No. 3/1/2/241/2021-Nut], Department of Science & Technology-Fund for Improvement of Science &Technology Infrastructure in Universities and Higher Educational Institutions (DST-FIST) grant [SR/FIST/LS-1/2019/502], and Department of Science & Technology -Promotion of University Research and Scientific Excellence (DST-PURSE) grant [SR/PURSE/2021/77] at Amity University, Rajasthan, Jaipur, India. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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