Table Info

Table 1.

A summary of the functions of autophagy-related circRNAs

circRNAs	Expression	Regulation targets and pathways	Influence on autophagy	Diseases	Refs
circCDYL	Up	circCDYL/miR-1275/ATG7/ULK1 axis	Enhancement	Breast cancer	[76]
circCUL2	Down	circCUL2/miR-142-3p/ROCK2 axis	Enhancement	Gastric cancer	[80]
circHIPK3	Down	circHIPK3/miR-124-3p/STAT3/PRKAA axis	Enhancement	Lung cancer	[81]
circHECTD1	Up	circHECTD1/miR-142/TIPARP axis	Enhancement	Cerebral ischemic stroke	[46]
circSHOC2	Up	circSHOC2/miR-7670-3p/SIRT1 axis	Suppression	Cerebral ischemic stroke	[75]
circ_002581	Up	circ_002581/miR-122/CPEB1 axis	Suppression	Nonalcoholic steatohepatitis	[82]

circCDYL: circular RNA CDYL; ULK1: UNC-51-like kinase 1; circCUL2: circular RNA CUL2; ROCK2: rho-associated coiled-coil-containing protein kinase-2; circHIPK3: circular RNA HIPK3; STAT3: signal transducer and activator of transcription 3; PRKAA: protein kinase AMP-activated catalytic subunit alpha 2; TIPARP: TCDD inducible poly[ADP-ribose] polymerase; circSHOC2: circular RNA SHOC2; SIRT1: sirtuin 1; CPEB1: cytoplasmic polyadenylation element-binding 1

Declarations

Author contributions

YH and LG: Investigation, Writing—original draft, Writing—review & editing. BH: Conceptualization, Validation, Writing—review & editing. HY: Conceptualization, Validation, Writing—review & editing, Supervision. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

This work was supported by the Science and Technology innovation 2030-Major Project of the Ministry of Science and Technology of China [2021ZD0202904/2021ZD0202900], the National Natural Science Foundation of Distinguished Young Scholars [82025033], the National Natural Science Foundation of China [82230115, 82003733], the Natural Science Foundation of Jiangsu Province [BK20200358], the Fundamental Research Funds for the Central Universities [2242021R40023], the Jiangsu Provincial Doctors of Entrepreneurship and Innovation Program. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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