| 1 |
2025 |
Zydrune Polianskyte-Prause, Amita Arora, Juuso H. Taskinen, Vaishali Chaurasiya, Salla Keskitalo, Antti Tuhkala, Ida Hilska, Markku Varjosalo, Vesa M. Olkkonen. The role of Nir2, a lipid-transfer protein, in regulating endothelial cell functions, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2025; 1872: 119926119926.
https://doi.org/10.1016/j.bbamcr.2025.119926 |
| 2 |
2025 |
Aniket Sen, Shilpa Thakur, Priya Rawat, Kajal Jaswal, Budheswar Dehury, Prosenjit Mondal. Hepatic ChREBP reciprocally modulates systemic insulin sensitivity in NAFLD, Journal of Biological Chemistry. 2025; 108556108556.
https://doi.org/10.1016/j.jbc.2025.108556 |
| 3 |
2025 |
Katarzyna Wiszniewska, Małgorzata Wilk, Małgorzata Wiszniewska, Joanna Poszwa, Oliwia Szymanowicz, Wojciech Kozubski, Jolanta Dorszewska. Kinesiotherapeutic Possibilities and Molecular Parameters in Multiple Sclerosis, Sclerosis. 2025; 3: 13.
https://doi.org/10.3390/sclerosis3020013 |
| 4 |
2022 |
Qingfang Li, Zhihui Li, Ting Luo, Huashan Shi. Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapy, Molecular Biomedicine. 2022; 3: 47.
https://doi.org/10.1186/s43556-022-00110-2 |
| 5 |
2025 |
Vandana Bhatia, Vir Vikram, Anjali Chandel, Aditya Rattan. Interplay between PI3k/AKT signaling and caspase pathway in Alzheimer disease: mechanism and therapeutic implications, Inflammopharmacology. 2025; 33: 1785.
https://doi.org/10.1007/s10787-025-01715-z |
| 6 |
2025 |
Jasper Hoi Chun Luong, Io Hong Cheong, Xue Feng Zhang, Zisis Kozlakidis, Hui Wang. Structure and Roles of Phospholipase C (PLC), Phosphatidylinositol 4,5-bisphosphate (PIP2), and Inositol 1,4,5-trisphosphate (IP3) in Metabolism and Disease: A Systematic Review, Innovations in Digital Health, Diagnostics, and Biomarkers. 2025; 5: 1.
https://doi.org/10.36401/IDDB-24-7 |
| 7 |
2024 |
Hua Su, Chao Peng, Yang Liu. Regulation of ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer, Frontiers in Cell and Developmental Biology. 2024; 12: 1372330.
https://doi.org/10.3389/fcell.2024.1372330 |
| 8 |
2023 |
Rahul Kumar, Rakesh Kumar, Harsh Goel, Sonu Kumar, Somorjit Singh Ningombam, Imran Haider, Usha Agrawal, Svs Deo, Ajay Gogia, Atul Batra, Ashok Sharma, Sandeep Mathur, Amar Ranjan, Anita Chopra, Showket Hussain, Pranay Tanwar. Whole exome sequencing identifies novel variants of PIK3CA and validation of hotspot mutation by droplet digital PCR in breast cancer among Indian population, Cancer Cell International. 2023; 23: 236.
https://doi.org/10.1186/s12935-023-03075-6 |
| 9 |
2023 |
Ana Bura, Sara Čabrijan, Iris Đurić, Tea Bruketa, Antonija Jurak Begonja. A Plethora of Functions Condensed into Tiny Phospholipids: The Story of PI4P and PI(4,5)P2, Cells. 2023; 12: 1411.
https://doi.org/10.3390/cells12101411 |
| 10 |
2025 |
S.G. Gaidin, S.A. Maiorov, V.P. Zinchenko, D.P. Laryushkin, S.T. Tuleukhanov, B.K. Kairat, A.M. Kosenkov. Pharmacological inhibition of PLC and PKC triggers epileptiform activity in hippocampal neurons, Epilepsy Research. 2025; 214: 107570107570.
https://doi.org/10.1016/j.eplepsyres.2025.107570 |
| 11 |
2025 |
Salvatore Incontro, Maria Laura Musella, Malika Sammari, Coralie Di Scala, Jacques Fantini, Dominique Debanne. Lipids shape brain function through ion channel and receptor modulations: physiological mechanisms and clinical perspectives, Physiological Reviews. 2025; 105: 137.
https://doi.org/10.1152/physrev.00004.2024 |
| 12 |
2023 |
Jianliang Li, Jiale Mai, Meng Zhang, Yanhuai Ma, Qi He, Dawei Gong, Jiacong Xiao, Miao Li, Weijian Chen, Zhen Li, Shuai Chen, Zhaofeng Pan, Shaocong Li, Haibin Wang. Myricitrin promotes osteogenesis and prevents ovariectomy bone mass loss via the PI3K/AKT signalling pathway, Journal of Cellular Biochemistry. 2023; 124: 1155.
https://doi.org/10.1002/jcb.30439 |
| 13 |
2024 |
Vaijayanthi Saravanan, Vinoj Gopalakrishnan, Maria Infant Majula Shifani Mahendran, Rajan Vaithianathan, Sowmya Srinivasan, Vinoth Boopathy, SriKrishna Krishnamurthy. Biofilm mediated integrin activation and directing acceleration of colorectal cancer, APMIS. 2024; 132: 688.
https://doi.org/10.1111/apm.13466 |
| 14 |
2023 |
Mykhailo Girych, Waldemar Kulig, Giray Enkavi, Ilpo Vattulainen. How Neuromembrane Lipids Modulate Membrane Proteins: Insights from G-Protein-Coupled Receptors (GPCRs) and Receptor Tyrosine Kinases (RTKs), Cold Spring Harbor Perspectives in Biology. 2023; 15: a041419.
https://doi.org/10.1101/cshperspect.a041419 |
| 15 |
2024 |
Jiaxu Chen, Zhaoping Pan, Qili Li, Yanyang Wu, Xiaopeng Li, Xue Wang, Dandan Hao, Xiaoyu Peng, Lina Pan, Wei Li, Jiaqi Wang, Tao Li, Fuhua Fu. The Aqueous Extract of Hemerocallis citrina Baroni Improves the Lactation-Promoting Effect in Bovine Mammary Epithelial Cells through the PI3K-AKT Signaling Pathway, Foods. 2024; 13: 2813.
https://doi.org/10.3390/foods13172813 |
| 16 |
2024 |
Sema Erisis, Marcel Hörning. Self-organization of PIP3 waves is controlled by the topology and curvature of cell membranes, Biophysical Journal. 2024; 123: 1058.
https://doi.org/10.1016/j.bpj.2024.03.022 |
| 17 |
2024 |
Young Keun Hwang, Dong-Hun Lee, Eun Chae Lee, Jae Sang Oh. Importance of Autophagy Regulation in Glioblastoma with Temozolomide Resistance, Cells. 2024; 13: 1332.
https://doi.org/10.3390/cells13161332 |
| 18 |
2024 |
Rahul Dubey, Anushka Sharma, Shankar Gupta, G.D. Gupta, Vivek Asati. A comprehensive review of small molecules targeting PI3K pathway: Exploring the structural development for the treatment of breast cancer, Bioorganic Chemistry. 2024; 143: 107077107077.
https://doi.org/10.1016/j.bioorg.2023.107077 |
| 19 |
2025 |
Mohammad Muzaffar Mir, Mohammed Jeelani, Muffarah Hamid Alharthi, Syeda Fatima Rizvi, Shahzada Khalid Sohail, Javed Iqbal Wani, Zia Ul Sabah, Waad Fuad BinAfif, Partha Nandi, Abdullah M. Alshahrani, Jaber Alfaifi, Adnan Jehangir, Rashid Mir. Unraveling the Mystery of Insulin Resistance: From Principle Mechanistic Insights and Consequences to Therapeutic Interventions, International Journal of Molecular Sciences. 2025; 26: 2770.
https://doi.org/10.3390/ijms26062770 |
| 20 |
2025 |
Guglielmo Lentini, Alessandro Querqui, Alessandro Giuliani, Roberto Verna, Mariano Bizzarri. Inositol and PIP2/PIP3 Ratio: At the Crossroad of the Biodynamic Interface Between Cells and Their Microenvironment, Biomolecules. 2025; 15: 451.
https://doi.org/10.3390/biom15030451 |
| 21 |
2023 |
Maria Derkaczew, Piotr Martyniuk, Robert Hofman, Krzysztof Rutkowski, Adam Osowski, Joanna Wojtkiewicz. The Genetic Background of Abnormalities in Metabolic Pathways of Phosphoinositides and Their Linkage with the Myotubular Myopathies, Neurodegenerative Disorders, and Carcinogenesis, Biomolecules. 2023; 13: 1550.
https://doi.org/10.3390/biom13101550 |
| 22 |
2022 |
Kamran Tariq, Erin Cullen, Stephanie A. Getz, Andie K.S. Conching, Andrew R. Goyette, Mackenzi L. Prina, Wei Wang, Meijie Li, Matthew C. Weston, Bryan W. Luikart. Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss, Cell Reports. 2022; 41: 111574111574.
https://doi.org/10.1016/j.celrep.2022.111574 |
| 23 |
2024 |
K.M. Abdullah, Gunjan Sharma, Faizan Abul Qais, Imran Khan, Simran Takkar, Jyoti B. Kaushal, Ranjana K Kanchan, Tarique Sarwar, Bandana Chakravarti, Jawed A Siddiqui. Hydroxychloroquine interaction with phosphoinositide 3-kinase modulates prostate cancer growth in bone microenvironment: In vitro and molecular dynamics based approach, International Journal of Biological Macromolecules. 2024; 266: 130912130912.
https://doi.org/10.1016/j.ijbiomac.2024.130912 |
| 24 |
2022 |
Sabrina Hupp, Christina Förtsch, Franziska Graber, Timothy J. Mitchell, Asparouh I. Iliev. Pneumolysin boosts the neuroinflammatory response to Streptococcus pneumoniae through enhanced endocytosis, Nature Communications. 2022; 13: 5032.
https://doi.org/10.1038/s41467-022-32624-2 |
| 25 |
2024 |
Shaofeng Yang, Donghai Li. Role of microRNAs in triple‑negative breast cancer and new therapeutic concepts (Review), Oncology Letters. 2024; 28: 431.
https://doi.org/10.3892/ol.2024.14565 |
| 26 |
2024 |
Sema Erisis, Marcel Hörning. 2024;
https://doi.org/10.1101/2024.01.20.576405 |
| 27 |
2023 |
Tomas Venit, Oscar Sapkota, Wael Said Abdrabou, Palanikumar Loganathan, Renu Pasricha, Syed Raza Mahmood, Nadine Hosny El Said, Shimaa Sherif, Sneha Thomas, Salah Abdelrazig, Shady Amin, Davide Bedognetti, Youssef Idaghdour, Mazin Magzoub, Piergiorgio Percipalle. Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice, Nature Communications. 2023; 14: 6328.
https://doi.org/10.1038/s41467-023-42093-w |
| 28 |
2024 |
Rujue Peng, Yujie Zhan, Anqi Li, Qiaoli Lv, Shan Xu. Research progress and development strategy of PI3K inhibitors for breast cancer treatment: A review (2016-present), Bioorganic Chemistry. 2024; 153: 107934107934.
https://doi.org/10.1016/j.bioorg.2024.107934 |
| 29 |
2024 |
Jason A. Weesner, Ida Annunziata, Diantha van de Vlekkert, Camenzind G. Robinson, Yvan Campos, Ashutosh Mishra, Leigh E. Fremuth, Elida Gomero, Huimin Hu, Alessandra d’Azzo. Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model, Cell Reports. 2024; 43: 114117114117.
https://doi.org/10.1016/j.celrep.2024.114117 |
| 30 |
2022 |
Ines Schmidts, Torsten Haferlach, Gregor Hoermann. 2022; 280: 35.
https://doi.org/10.1007/164_2022_608 |
| 31 |
2024 |
Daniel Birtles, Jinwoo Lee. Exploring the influence of anionic lipids in the host cell membrane on viral fusion, Biochemical Society Transactions. 2024; 52: 2593.
https://doi.org/10.1042/BST20240833 |
