Hydrogel based wound dressing systems for localized drug delivery.
| Hydrogel system | Therapeutic function | Role | Mechanism | Application |
|---|---|---|---|---|
| Chitosan based hydrogel [13] | Antibacterial/anti-inflammatory agents | Infection control and inflammation reduction | Diffusion, degradation, or pH-responsive release | Infected and diabetic wounds |
| Alginate based hydrogel [14] | Antimicrobials, growth factors, ions | Exudate absorption and moist healing | Swelling controlled release | Exuding wounds |
| Hyaluronic acid hydrogel [15] | Growth factors, antioxidants, peptides | Cell migration and tissue regeneration | Enzyme- or degradation-mediated release | Chronic wounds |
| Gelatin/collagen hydrogel [16] | Growth factors, cells, hemostatic agents | ECM support and granulation tissue formation | Entrapment and sustained diffusion | Regenerative wound dressings |
| Composite hydrogel [16] | Antimicrobials, antioxidants, nanozymes | Multifunctional wound repair | Combined swelling, degradation, and stimuli response | Infected diabetic wounds |
| Self-healing hydrogel [17] | Antibacterial nanoparticles or peptides | Adhesion, flexibility, and repeated wound movement | Dynamic covalent/reversible bonding | Irregular or mobile wound sites |
During the preparation of this work, the authors used the Grammarly tool for language editing, grammar improvement, and formatting assistance. After utilizing the tool/service, the authors reviewed and edited the content as necessary and take full responsibility for the final content of the publication.
MF: Conceptualization, Supervision, Methodology, Investigation, Data curation, Visualization, Writing—original draft, Writing—review & editing. SS: Conceptualization, Formal analysis, Validation, Writing—review & editing. Both authors read and approved the final manuscript.
The authors declare that they have no conflicts of interest.
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