The authors gratefully acknowledge the King Abdullah International Medical Research Center (KAIMRC), Saudi Arabia, for generously providing the cell lines used in this study.
Author contributions
S Alhabardi: Conceptualization, Methodology, Investigation, Writing—original draft, Supervision, Project administration. A Almurshedi: Methodology, Investigation, Data curation, Writing—review & editing. S Alnassar: Formal analysis, Investigation, Writing—review & editing. S Alshabanah: Data curation, Visualization, Writing—review & editing. NA: Resources, Investigation. A Alotaibi: Validation, Data curation. LA: Software, Formal analysis. S Alahmari: Resources, Investigation. A Alanteet: Resources, Investigation. All authors have read and approved the submitted version.
Conflicts of interest
The authors declare that they have no conflicts of interest.
Ethical approval
Not applicable.
Consent to participate
Not applicable.
Consent to publication
Not applicable.
Availability of data and materials
The raw data supporting the conclusions of this manuscript will be made available by the authors.
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Ruckmani K, Sankar V. Formulation and optimization of Zidovudine niosomes.AAPS PharmSciTech. 2010;11:1119–27. [DOI] [PubMed] [PMC]
Moammeri A, Chegeni MM, Sahrayi H, Ghafelehbashi R, Memarzadeh F, Mansouri A, et al. Current advances in niosomes applications for drug delivery and cancer treatment.Mater Today Bio. 2023;23:100837. [DOI] [PubMed] [PMC]
Taymouri S, Varshosaz J. Effect of different types of surfactants on the physical properties and stability of carvedilol nano-niosomes.Adv Biomed Res. 2016;5:48. [DOI] [PubMed] [PMC]
Deulkar DA, Kubde JA, Hatwar PR, Bakal RL, Motwani AN. Niosomes: A promising approach for targeted drug delivery.GSC Biol Pharm Sci. 2024;29:179–95. [DOI]
Riccardi D, Baldino L, Reverchon E. Liposomes, transfersomes and niosomes: production methods and their applications in the vaccinal field.J Transl Med. 2024;22:339. [DOI] [PubMed] [PMC]
Witika BA, Bassey KE, Demana PH, Siwe-Noundou X, Poka MS. Current Advances in Specialised Niosomal Drug Delivery: Manufacture, Characterization and Drug Delivery Applications.Int J Mol Sci. 2022;23:9668. [DOI] [PubMed] [PMC]
Lamb YN. Osimertinib: A Review in Previously Untreated, EGFR Mutation-Positive, Advanced NSCLC.Target Oncol. 2021;16:687–95. [DOI] [PubMed] [PMC]
Lin Y, Hsiao C, Alshetaili A, Aljuffali IA, Chen E, Fang J. Lipid-based nanoformulation optimization for achieving cutaneous targeting: Niosomes as the potential candidates to fulfill this aim.Eur J Pharm Sci. 2023;186:106458. [DOI] [PubMed]
Gaikwad DS, Chougale RD, Patil KS, Disouza JI, Hajare AA. Design, development, and evaluation of docetaxel-loaded niosomes for the treatment of breast cancer.Futur J Pharm. 2023;9:43. [DOI]
Liga S, Paul C, Moacă E, Péter F. Niosomes: Composition, Formulation Techniques, and Recent Progress as Delivery Systems in Cancer Therapy.Pharmaceutics. 2024;16:223. [DOI] [PubMed] [PMC]
Nowroozi F, Almasi A, Javidi J, Haeri A, Dadashzadeh S. Effect of Surfactant Type, Cholesterol Content and Various Downsizing Methods on the Particle Size of Niosomes.Iran J Pharm Res. 2018;17:1–11. [PubMed] [PMC]
Mowlaeifar MH, Niakousari M, Hosseini SMH, Eskandari MH. Effect of Cholesterol to Vitamin D3 and Span 60 to Tween 60 Ratios on the Characteristics of Niosomes: Variable Optimization Using Response Surface Methodology (RSM).J Food Qual. 2022;2022:7005531. [DOI]
Zolghadri S, Asad AG, Farzi F, Ghajarzadeh F, Habibi Z, Rahban M, et al. Span 60/Cholesterol Niosomal Formulation as a Suitable Vehicle for Gallic Acid Delivery with Potent In Vitro Antibacterial, Antimelanoma, and Anti-Tyrosinase Activity.Pharmaceuticals (Basel). 2023;16:1680. [DOI] [PubMed] [PMC]
Khaliq NU, Lee J, Kim S, Sung D, Kim H. Pluronic F-68 and F-127 Based Nanomedicines for Advancing Combination Cancer Therapy.Pharmaceutics. 2023;15:2102. [DOI] [PubMed] [PMC]
Gao S, Sui Z, Jiang Q, Jiang Y. Functional Evaluation of Niosomes Utilizing Surfactants in Nanomedicine Applications.Int J Nanomedicine. 2024;19:10283–305. [DOI] [PubMed] [PMC]
Kazi KM, Mandal AS, Biswas N, Guha A, Chatterjee S, Behera M, et al. Niosome: A future of targeted drug delivery systems.J Adv Pharm Technol Res. 2010;1:374–80. [DOI] [PubMed] [PMC]
