Table Info

Table 1.

Clinical features of SFN in the presence of normal muscle strength, proprioception and tendon reflexes

Sensory	Autonomic
Positive sensory symptoms: tingling, burning, prickling, shooting pain, or aching Worse at night, interfering with sleep Allodynia Hyperesthesia Cramps Numbness, tightness Sensation of coldness Impaired thermal and pain sensitivity	Increased/decreased sweating Facial flushing Skin discolouration Dry eyes and mouth Orthostatic hypotension Urinary symptoms of hesitancy, incomplete emptying Enteric symptoms of constipation, diarrhea, abdominal distension, food intolerance Miosis and tonic pupils

Sensory

Autonomic

Positive sensory symptoms: tingling, burning, prickling, shooting pain, or aching

Worse at night, interfering with sleep

Allodynia

Hyperesthesia

Cramps

Numbness, tightness

Sensation of coldness

Impaired thermal and pain sensitivity

Increased/decreased sweating

Facial flushing

Skin discolouration

Dry eyes and mouth

Orthostatic hypotension

Urinary symptoms of hesitancy, incomplete emptying

Enteric symptoms of constipation, diarrhea, abdominal distension, food intolerance

Miosis and tonic pupils

Declarations

Author contributions

ACYC, KO, and JV: Conceptualization. KO, ACYC, JV: Writing—original draft, Writing—review & editing. All authors contributed to manuscript revision, read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

ACYC is supported by the Singapore Ministry of Health’s National Medical Research Council [MOH-000437-0] under its NMRC Research Training Fellowship. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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