Baseline characteristics of participants in the synbiotic and control groups.
| Baseline characteristics | Synbiotic group | Control group | p value |
|---|---|---|---|
| n | 9 | 10 | - |
| Sex (female/male) | 6/3 | 7/3 | - |
| Age (years) | 79.33 ± 4.5 | 74.99 ± 6.6 | 0.11 |
| Baseline results (points) | |||
| Mini-Mental State Examination | 16.78 ± 0.97 | 16.10 ± 2.08 | 0.1923 |
| Rey-Osterrieth Complex Figure Test-memory | 11.06 ± 3.45 | 10.90 ± 2.75 | 0.9142 |
| Rey-Osterrieth Complex Figure Test-copy | 24.74 ± 7.22 | 24.70 ± 6.71 | 0.9891 |
| AERAC test | 68.52 ± 5.06 | 67.69 ± 6.62 | 0.4626 |
AERAC: Abbreviated Instrument for Expectations of Self-Efficacy for Daily Activities in Older Adults.
OMDC, AEC, NRS, and EMG: Conceptualization, Investigation, Data curation. APIG, IIM, EMAM, and MAVH: Data curation, Validation. MPHV, PRE, SGSÁ, and MESH: Writing—original draft, Visualization, Writing—review & editing. AI: Supervision, Project administration, Funding acquisition, Writing—review & editing, Writing—original draft, Formal analysis. All authors read and approved the submitted version.
Antonio Ibarra, who is the Editorial Board Member and Guest Editor of Exploration of Neuroprotective Therapy, Andrea P. Ibarra García who is the Guest Editor of Exploration of Neuroprotective Therapy, had no involvement in the decision-making or the review process of this manuscript. The other authors declare no conflicts of interest.
The study was approved by the Universidad Anáhuac México, Campus Norte, Ethics on Research Committee, Faculty of Health Sciences (Approval ID: CONBIOETICA-15-CEI-004-20160729). The trial was registered at ClinicalTrials.gov (NCT05688618).
Informed consent to participate in the study was obtained from all participants.
Not applicable.
The datasets supporting the findings of this study are available from the corresponding author upon reasonable request.
This work was supported by the research support fund number [202007], Universidad Anáhuac (awarded to Antonio Ibarra). The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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