Table Info

Table 3.

The effects of herbal formulas on psoriasis

Formula	Composition Plant		Extract method	*In vitro*	*In vivo*	Signaling pathway(s)	Target(s)	Reference
Formula	Plant	Used part	Extract method	*In vitro*	*In vivo*	Signaling pathway(s)	Target(s)	Reference
Bai Xuan Xia Ta Re Pian	Euphorbiae humifusae L.	Aerial part	-	-	Mice	Th17 cell differentiation	IL-17, IL-23	[40]
	Terminalia chebula Retz.	Young fruit Ripe fruit
	Terminalia bellirica Roxb.	Fruit
	Aloe vera	Leaf
	Convolvulus scammonia	Resin
Dang Gui Liu Huang Tang	Angelica acutiloba Kitag.	Root	EtOH	HaCaT	Mice	MAPK; STAT3	IL-22, CXCL10, K16, K17, Ki67	[76]
	Rehmannia glutinosa Libosch.
	Scutellaria baicalensis Georgi.
	Astragalus membranaceus Bunge.
	Coptis chinensis Franch.
	Phellodendron amurense Rupr.	Peel
Gold lotion	Citrus sinensis	Peel	EtOH	DCs	Mice	Th17 cell differentiation	IL-17, IL-22	[39]
	Citrus hassaku
	Citrus limon
	Citrus natsudaidai
	Citrus miyauchi Iyo
	Citrus unshiu
PAMs	Carthamus tinctorius	-	EtOH	HaCaT	Mice	NF-κB	IL-8, TNF-α, ICAM-1, IL-23	[54]
	Lithospermum erythrorhizon
	Solanum indicum
	Cymbopogon distans
PSORI-CM01	Curcuma zedoaria	Rhizome	-	HaCaT	Mice	NF-κB; Th17 cell differentiation	IL-6, IL-8, CXCL10, CCL20	[100]
	Sarcandra glabra	Aerial part
	Smilax glabra Roxb.	Rhizome
	Prunus mume	Fruit
	Arnebia euchroma (Royle) Johnst.	Root
	Paeonia lactiflora
	Glycyrrhiza uralensis
PSORI-CM02	Smilax glabra Roxb.	Rhizome	Water	HaCaT	Mice	PI3K/Akt/mTOR	Beclin1, Atg 7, Atg 16L1, Atg 3	[78]
	Sarcandra glabra (Thunb.) Nakai	Leaf		HaCaT		PI3K/Akt/mTOR	Beclin1, Atg 7, Atg 16L1, Atg 3	[78]
	Paeonia lactiflora Pall	Root		RAW264.7		STAT1; STAT6	TNF-α, iNOS, IL-1β	[77]
	Curcuma phaeocaulis Val.	Root
	Prunus mume Sieb. et Zucc.	Fruit
Psoriasis 1	Smilacis glabrae	Rhizome	-	HaCaT	Rat	NF-κB; STAT	TNF-α, IFN-γ, IL-22, IL-17, IL-1β, IL-4	[102]
	Folium isatidis	Leaf
	Isatis tinctoria L.	Root
	Angelica sinensis	Root
	Hedyotis diffusa	Aerial part
	Ligusticum striatum	Rhizome
	Plantago major	Leaf		PBMCs	-	STAT4	IL-17, IL-23, TNF-α, IFN-γ, IL-2, IL-6, IL-4, TGF-β	[101]
	Kochia scoparia	Fruit
	Lobelia chinensis	Aerial part
	Alisma orientale	Rhizome
	Dictamnus dasycarpus Turcz.	Cortex
	Glycyrrhiza uralensis	Root

Atg7: autophagy related 7; PAMs: plant antimicrobial solutions; TGF-β: transforming growth factor-beta; -: not applicable

Declarations

Author contributions

The author contributed solely to the work.

Conflicts of interest

The author declares that there are no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

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Copyright

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