AOS in obesity and IR in human studies

Human tissue/cell typeComponents of AOS defenseEffect of obesity/IRRef
Serum of obese womenGPx activityDecreased[85]
Plasma of obese children of both sexesZn concentrationDecreased[93]
Serum of morbidly obese male and female patientsVitamins A, B6, C, D, E concentrationsDecreased[95]
Serum of obese adolescentsSe concentrationDecreased[92]
Erythrocytes of obese womenCu/Zn-SOD, CAT, GPx activitiesDecreased[86]
Serum of male and female T2DM patientsGSH content/GPx, GR activitiesDecreased[32]
Adipose tissue of obese and/or T2DM male and female patientsMn-SOD, GPx activitiesDecreased[87]
Serum and liver of male and female NAFLD patientsGSH levelDecreased[33]
Peripheral blood mononuclear cells of obese children of both sexesMn-SOD, CAT expressionDecreased[34]
Serum of MS male and female patientsVitamin E concentrationDecreased[96]
Blood samples of obese and overweight childrenSOD activity/GSH/GSSG ratio, CAT activityIncreased/decreased (in obese); all decreased (in overweight)[88]
Blood samples of MS male and female patientsVitamin C, GSH levelsDecreased[89]

NAFLD: non-alcoholic fatty liver disease