Fetal/perinatal effects and complications in which demonstrable effects of chronic HBV infection have been reported

Fetal and perinatal effects and complicationsEffect of maternal HBV carrier statusReferences
Spontaneous miscarriageIncreased[25, 54, 66]
Fetal congenital malformationsIncreased[23, 50, 54]
Intrauterine fetal demise (IUFD), stillbirth (SB), and perinatal mortalityIncreased[12, 23, 54]
Low birthweight (LBW) and small-for-gestational age (SGA) infantsIncreased LBW infants[11, 23, 54, 67]
Increased in HBeAg positive[13]
Increased SGA infants[11, 67]
Reduced[11, 18, 28, 68]
Reduced SGA in CD[27]
Large-for-gestational age (LGA) and macrosomic infantsIncreased birthweight in Oriental Chinese women[24, 47]
Increased LGA/macrosomia[12, 48, 68]
Increased in HBeAg negative[26]
Fetal distress and birth asphyxiaIncreased[22, 23, 48, 56]