From:  Associations of polypharmacy with cognitive impairment and functional status among older adults

 Comparison of general characteristics according to polypharmacy status.

Variables0–4 drugs
(n = 9,422)
N (%)
≥ 5 drugs
(n = 476)
N (%)
*p-value
Sex0.001
Male4,192 (44.5)175 (36.8)
Female5,230 (55.5)301 (63.2)
Age group (years)< 0.001
65–693,391 (36.0)73 (15.3)
70–793,853 (40.9)225 (47.3)
≥ 802,178 (23.1)178 (37.4)
Education< 0.001
≤ Middle school5,663 (60.1)397 (83.4)
High school3,072 (32.6)62 (13.0)
≥ University687 (7.3)17 (3.6)
Household income< 0.001
Low6,033 (64.0)381 (80.0)
Middle1,610 (17.1)51 (10.7)
High1,779 (18.9)44 (9.3)
Employment status< 0.001
Unemployed5,619 (59.6)369 (77.5)
Employed3,803 (40.4)107 (22.5)
Current smoker0.500
No8,521 (90.4)435 (91.4)
Yes901 (9.6)41 (8.6)
Alcohol consumption< 0.001
No5,790 (61.5)378 (79.4)
Yes3,632 (38.5)98 (20.6)
Regular exercise0.003
No4,391 (46.6)256 (53.7)
Yes5,031 (53.4)220 (46.3)
Number of chronic diseases2 (2)5 (2)< 0.001

*p-values were calculated using chi-square tests for categorical variables and the Mann-Whitney U test for continuous variables. All analyses applied sampling weights. Due to weighting procedures and rounding, the sums of frequencies and percentages may not exactly match the group totals or equal 100%.