From:  Repurposing the anti-breast cancer drug Tamoxifen: antibacterial and antibiofilm efficacy of novel Tamoxifen-AgNP conjugate against multidrug-resistant healthcare-associated pathogens

 MIC of Tamoxifen, AgNPs, and their combinations (AgNP-T complex) against E. faecalis, S. aureus, and E. coli.

AgentsOrganisms
S. aureusE. faecalisE. coli
Tamoxifen31 µg/mL125 µg/mL62.5 µg/mL
AgNPs5 µg/mL5 µg/mL2.5 µg/mL
AgNP-T1.25 µg/mL of AgNP and 7.75 µg/mL of T1.25 µg/mL of AgNP and 31 µg/mL of T0.625 µg/mL of AgNP and 15.5 µg/mL of T

MIC: minimal inhibitory concentration; AgNPs: silver nanoparticles; AgNP-T: AgNP-Tamoxifen complex; T: Tamoxifen.