Exploration of Medicine

Table 1. General characteristics of the groups of patients

Indicator	Group 1 АН without MS (n = 23)	Group 2 AН and MS (n = 25)	Group 3 AН and DМ (n = 10)
Men/Women (n)	11/12	11/14	1/9
Age, years	53.3 (40.9; 66.3)	54.6 (44.7; 65.8)	63.6 (49.3; 72.8)^∆
BMI, kg/m²	26.1 (20.3; 29.2)	32.3 (30.7; 37.2)^#	33.6 (32.5; 37.6)^∆
SBP office, mmHg	162.7 (148.0; 173.0)	163.2 (146.0; 172.0)	166.2 (145.0; 180.0)
DBP office, mmHg	95.6 (87.0; 102.0)	98.7 (86.0; 108.0)	99.7 (90.0; 105.0)
HR, bpm	72.6 ± 9.4	74.6 ± 7.3	77.0 ± 10.6
Components of metabolic syndrome
Waist circumference (women), cm Waist circumference (men), cm Additional, % (n) BP over 140/90 mmHg Glycemia (≥ 6.1 and < 7 mmol/L) Triglycerides (≥ 1.7 mmol/L) HDL (< 1.0 mmol/L) LDL (> 3.0 mmol/L)	77.6 (74; 79) 90.3 (82; 91) 100.0 30.4 4.3 91.3 95.7	89.3 (82; 100) 101.6 (88; 118)^# 100.0 64.0 24.0 80.0 100.0	96.4 (86; 110)^∆ 103.0 (93; 127)^∆ 100.0 0.0 20.0 100.0 100.0

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^# P < 0.05 comparing groups 1 and 2; ^∆ P < 0.05 comparing groups 1 and 3. Quantitative data are presented as the median Me, 25 and 75 percentiles (LQ, UQ), and in the form of M ± m, where M is the mean value, m is the standard deviation in the case of their normal distribution. AH: arterial hypertension; MS: metabolic syndrome; DM: diabetes mellitus; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; BP: blood pressure; HDL: high-density lipoprotein; LDL: low-density lipoprotein

Declarations

Author contributions

AAS: Conceptualization, Writing—review & editing. MAO: Conceptualization, Investigation, Writing—original draft, Writing—review & editing. INV: Conceptualization, Investigation, Project administration, Validation, Writing—original draft, Writing—review & editing. MVT: Project administration, Writing—original draft. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

The study was carried out taking into account international rules and ethical standards developed on the basis of the World Medical Association’s Declaration of Helsinki «Ethical Principles for Medical Research Involving Human Subjects». The study was approved by the Local Ethics Committee of Sechenov University (Extract from the Protocol of the 17–24 meeting dated 04.07.2024).

Consent to participate

Informed consent to participate in the study was obtained from all participants.

Consent to publication

Informed consent to publication was obtained from relevant participants.

Availability of data and materials

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Funding

Not applicable.

Copyright

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