Summary of the properties and advantages of cell-derived vesicles
Platform | Properties | Advantages | Reference |
---|---|---|---|
Whole cell | Own the components and properties of cell, such as cell membrane, organelles, etc. | High loading capacity;Low immunogenicity;Good biocompatibility;Long circulation time. | [25, 33–35] |
Cell-derived membranous structures | Participate in cell-to-cell communication; Cannot replicate like cells;Carry proteins, nucleic acids, lipids and other substances from mother cells. | Wide variety of sources;Excellent targeting ability. | [30, 45–47] |
Both authors contributed to the writing of the manuscript, and edited the manuscript at all stages. JX was responsible for collecting and writing the manuscript. CW was responsible for writing, reviewing and editing the manuscript.
The authors declare that they have no conflicts of interest.
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This work was supported by grants from startup supports of Soochow University and the Program for Jiangsu Specially-Appointed Professors to CW. This work was also supported by National Natural Science Foundation of China (No. 31900988, 32022043), the Natural Science Foundation of Jiangsu Province (No. SBK2019040088) and Jiangsu Province Six Talent Peaks Project (No. SWYY-110). This work was partly supported by Collaborative Innovation Center of Suzhou Nano Science & Technology, the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), the 111 Project. The funders had a role in the design and preparation of the manuscript.
© The Author(s) 2021.