Regression analysis of prognostic factors for polyposis and hypertrophic changes of sinonasal mucosa in children and adolescents with asthma and allergic rhinitis
Data
AUC
95% CI
Sensitivity (%)
Specificity (%)
OR [95% CI]
P-value
ECP
0.715
0.715 ± 0.055
78.0
48.0
1.008 [1.002–1.013]
< 0.001
IL-4
0.674
0.674 ± 0.057
74.4
46.0
1.005 [1.001–1.008]
0.004
IL-1
0.638
0.638 ± 0.058
76.7
46.0
1.003 [1.000–1.006]
0.023
VEGF
0.541
0.541 ± 0.062
71.4
24.0
0.840 [0.332–0.939]
0.500
IgЕ
0.463
0.463 ± 0.062
69.0
22.0
0.694 [0.193–0.840]
0.538
AUC: area under the curve; OR: odds ratio; ECP: eosinophil cationic protein; IL-4: interleukin 4; IgE: immunoglobulin E; VEGF: vascular endothelial growth factor
Declarations
Author contributions
SVK: Conceptualization, Resources, Investigation, Methodology, Validation, Visualization, Writing—original draft, Writing—review & editing. TIE: Conceptualization, Investigation, Formal analysis, Supervision, Resources, Writing—original draft, Writing—review & editing. EIK and EAL: Resources, Investigation, Methodology. RNK: Data curation, Software. KVG: Resources, Data curation. DYO, NAG, and NIK: Writing—review & editing. All authors read and approved the final manuscript.
Conflicts of interest
The authors declare no competing interests.
Ethical approval
The study was approved by the Ethical Committee of the Volga Region Research Medical University (protocol No13, dated 10.10.2016).
Consent to participate
All participants and all primary caregivers gave written informed consent.
Consent to publication
Not applicable.
Availability of data and materials
The data used to support the findings of this study are available from the corresponding author (Svetlana Viktorovna Krasilnikova, mashkovasv@mail.ru) upon request.
Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.
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