Perspective classes, characteristic genes, and defining traits of AD patients

Perspective class Number of subjects Gene name Gene symbol Defining trait
I 156 Tubulin beta 1 class VI TUBB1 Vasculogenesis
Ankyrin repeat and SOCS box-containing protein 4 ASB4
Phosphodiesterase 5A PDE5A
II 164 Neuregulin-2 NRG2 Cell signaling and differentiation
Zinc-finger 3 ZNF3
III 84 Insulin-like growth factor 1 IGF1 Metabolism
Ankyrin repeat and SOCS box-containing protein 4 ASB4
G2 and S-phase expressed protein 1 GTSE1
IV 134 cDNA FLJ39269 Nitric oxide
Integrin subunit alpha ITGA1
Carboxypeptidase M CPM
V 76 Phosphodiesterase 5A PDE5A Mitochondrial
Presenilin 1 PSEN1
NADH-coenzyme Q reductase NDUFS8
VI 228 DDB1 and CUL4 associated factor 17 DCAF17 Metal ion transport
cDNA FLJ75819
Solute carrier family 33 member 1 SLC33AI

SOCS: suppressor of cytokine signaling; NADH: nicotinamide adenine dinucleotide; DDB1: DNA damage-binding protein 1; CUL4: cullin-4