Exploration of Medicine

Symptom domain gastrointestinal	ME/CFS Family history (n = 72)	ME/CFS No family history (n = 326)	Significance level
Bloating	51.74 (27.62)	44.98 (28.35)	0.07
Abdomen/stomach pain	50.69 (24.90)	39.14 (27.10)	< 0.01
Irritable bowel problems	54.69 (30.86)	46.15 (32.41)	0.04

Declarations

Author contributions

LAJ: Conceptualization, Investigation, Writing—original draft, Writing—review & editing, Supervision. SN: Investigation, Writing—original draft.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

The study was approved by the DePaul University Institutional Review Committee (PF020317PSY).

Consent to participate

Informed consent to participate in the study was obtained from all participants.

Consent to publication

Not applicable.

Availability of data and materials

The raw data supporting the conclusions of this manuscript will be made available by the authors, without undue reservation, to any qualified researcher.

Funding

Not applicable.

Copyright

References

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Symptom domain gastrointestinal	ME/CFS Family history (n = 72)	ME/CFS No family history (n = 326)	Significance level
Symptom domain gastrointestinal	mean (SD)	mean (SD)	Significance level
Bloating	51.74 (27.62)	44.98 (28.35)	0.07
Abdomen/stomach pain	50.69 (24.90)	39.14 (27.10)	< 0.01
Irritable bowel problems	54.69 (30.86)	46.15 (32.41)	0.04