Differences in DSQ-1 symptom domain scores among those with and without a ME/CFS family history

Symptom domainsME/CFS
Family history
(n = 72)
ME/CFS
No family history
(n = 328)
Significance level
mean (SD)mean (SD)
Sleep62.58 (20.23)61.06 (18.23)0.53
PEM73.36 (18.29)72.13 (17.02)0.58
Neurocognitive58.25 (20.66)60.12 (20.01)0.47
Immune36.62 (17.96)34.15 (18.84)0.31
Neuroendocrine38.66 (18.75)37.94 (20.79)0.79
Pain64.84 (26.31)63.18 (26.67)0.63
Gastrointestinal52.31 (23.19)43.37 (25.18)< 0.01
Orthostatic37.71 (16.79)35.05 (19.20)0.29

PEM: post-exertional malaise