Table Info

Table 1.

Characterization of gut dysbiosis in different autoimmune conditions compared to healthy or disease controls

Disease	Author	Study object	Study findings
Disease	Author	Study object	Increased microbiota	Decreased microbiota
BD	Yasar et al., 2020 [40]	27 BD vs. 10 HCs	Lachnospiraceae NK4A136, Actinomyces, Libanicoccus, Collinsella, Eggerthella, Enetrohabdus, Catenibacterium, Enterobacter	Bacteroides, Cricetibacter, Alistipes, Lachnospira, Dielma, Akkermansia, Sutterella, Anaerofilum, Ruminococcease-UCG007, Acetanaerobacterium, Copropaacter
	Shimizu et al., 2019 [41]	13 BD vs. 27 HCs	Eggerthella lenta, Acidaminococcus bifidum, Lactobacillus iners, Streptococcus species, Lactobacillus salivarius	Megamonas hypermegale, Butyrivibrio, Streptococcus infantis, Filifacto
	Oezguen et al., 2019 [42]	13 BD vs. 14 HCs	Parabacteroides, Clostridiales, Geminger, Butyricimonas, Actinobacteria, Erysipelotrichaceae	Vampirovibrio, unclassified Lachnospiraceae, Prevotella
	Ye et al., 2018 [33]	32 BD vs. 74 HCs	Bilophila spp., Parabacteroides spp., Paraprevotella spp., Stenotrophomonas spp., Actinomyces spp., Corynebacterium spp.	Clostridium spp. (BPB), Methanoculleus spp., Methanomethylophilus spp.
VKH	Ye et al., 2020 [39]	55 VKH vs. 52 HCs	Ramularia, Alternaria, Rhizophagus	Methanoculleus, Candidatus Methanomethylophilus, Azospirillum
VKH	Li et al., 2022 [43]	11 VKH vs. 11 HCs vs. 20 NIAS	Stomatobaculum, Pseudomonas, Lachnoanaerobaculum	Gordonibacter, Slackia
AS	Zhang et al., 2020 [44]	20 AS vs. 19 HCs	Prevotellaceae, Actinomycetaceae, Dialister, Escherichia-Shigella, Klebsiella	Lachnospiraceae, Bacteroides, Parasutterella, Bifidobacterium
	Yin et al., 2020 [45]	127 AS vs. 123 HCs	Clostridiales bacterium 1_7_47FAA, Clostridium hatheway, Clostridium bolteae	Bifidobacterium adolescentis, Coprococcus comes, Lachnospiraceae bacterium 5_1_63FAA, Roseburia inulinivorans
	Klingberg et al., 2019 [46]	150 AS vs. 17 HCs	Proteobacteria, Enterobacteriaceae, Bacilli, Streptococcus species, Actinobacteria	Bacteroides, Lachnospiraceae
IBD	Takahashi et al., 2016 [47]	10 IBD vs. 10 HCs	Actinomyces, Bifidobacterium	Bacteroides, Eubacterium, Faecalibacterium, Ruminococcus
IBD	Franzosa et al., 2019 [48]	121 IBD vs. 34 HCs	Bifidobacterium breve, Clostridium symbiosum, Ruminococcus gnavusa, Escherichia coli, Clostridium clostridioforme	Roseburia hominis, Dorea formicigenerans, Ruminococcus obeum

HCs: healthy controls; AS: ankylosing spondylitis; NIAS: non-infectious anterior scleritis

Declarations

Author contributions

HA and SS equally contributed to: Conceptualization, Writing—original draft, Writing—review & editing.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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