Table Info

Table 4.

Configuration of cognition, BP, and BMI

Cognition	BMI	SBP	Count	Expected count	Test statistic for asymptotic binomial test	Type
1	1	1	19	7.98	3.78^***	Type
1	1	2	2	6.46	−1.98
1	2	1	40	36.88	0.56
1	2	2	29	29.86	−0.17
1	3	1	14	20.36	−1.47
1	3	2	13	16.49	−0.89
1	4	1	6	5.50	0.00
1	4	2	5	4.46	0.26
2	1	1	5	8.04	−1.27
2	1	2	3	6.51	−1.59
2	2	1	37	37.16	−0.03
2	2	2	28	30.10	−0.41
2	3	1	19	20.52	−0.35
2	3	2	28	16.62	2.89^**	Type
2	4	1	2	5.55	−1.74
2	4	2	7	4.49	1.19

Blank spaces in the last column reflect neither types nor antitypes. The corresponding configurations are not different from expected values; ^** P < 0.01; ^*** P < 0.001. Cognition (1: < 23; 2 ≥ 23), BMI (1: < 18.5 kg/m²; 2: ≥ 18.5 kg/m² and < 23.0 kg/m²; 3: ≥ 23.0 kg/m² and < 30.0 kg/m²; 4: ≥ 30.0 kg/m²), SBP (1: < 130 mmHg; 2: ≥ 130 mmHg)

Declarations

Acknowledgments

Authors acknowledge the valuable recruitment and data acquisition effort by M. Burgess, K. Grier, E. Jackson, E. McCarthy, K. Shaw, L. Strong, and S. Reynolds, data acquisition team manager; S. Anderson, E. Cassidy, M. Janke, and J. Savla, data management; M. Poon, project fiscal management.

Author contributions

PM: Conceptualization, Formal analysis, Writing—original draft, Writing—review & editing. RA: Formal analysis, Writing—review & editing. MK: Conceptualization, Writing—review & editing. KG: Conceptualization, Writing—review & editing. YG: Writing—review & editing. MAJ: Conceptualization, Formal analysis, Writing—review & editing. LWP: Supervision Writing—review & editing. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflict of interest.

Ethical approval

The study was approved by the Institutional Review Boards (IRB) at the University of Georgia and Iowa State University (XX-026) and complied with Declaration of Helsinki.

Consent to participate

Informed consent to participate in the study was obtained from all participants.

Consent to publication

Not applicable.

Availability of data and materials

Data are available from the principal investigator of the study Leonard W. Poon (lpoon8122@gmail.com).

Funding

The Georgia Centenarian Study was funded by [1P01AG17553] from the National Institute on Aging, a collaboration among The University of Georgia, Tulane University Health Sciences Center, Boston University, University of Kentucky, Emory University, Duke University, Wayne State University, Iowa State University, Temple University, and University of Michigan. Additional investigators of the Georgia Centenarian Study include S. M. Jazwinski, R. C. Green, M. MacDonald, M. Gearing, W. R. Markesbery (deceased), J. L. Woodard, M. A. Johnson, J. S. Tenover, I. C. Siegler, W. L. Rodgers, D. B. Hausman, C. Rott, A. Davey, and J. Arnold. The first author’s work on the project was supported by the Fulbright Commission and by United States Department of Agriculture, Hatch Project Grant, [IOW04116]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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