Descriptive analysis on anthropometric, biochemical, and gynaecological profiles between PCOS cases and controls
Sl No.
Variable
Median (25–75% percentile) controln = 75
Median (25–75% percentile) PCOSn = 98
P value
1
Menarche (year)
13 (12–15)
13 (12–15)
0.71
2
Age (year)
28 (26–31)
28 (25–29)
0.20
3
BMI (kg/m2)
24 (22–25)
27 (24–30)
< 0.0001$
4
PRL (ng/mL)
11 (6.7–17)
14 (8.8–23)
< 0.05*
5
AMH (ng/mL)
1.8 (1.2–2.1)
5.1 (3.8–8.6)
< 0.0001$
6
FBS (mg/dL)
90 (85–93)
98 (81–105)
0.031*
7
2-h PG (mg/dL)
110 (102–121)
122 (107–145)
0.0001$
8
Hb (gm/dL)
12 (12–13)
12 (10–13)
0.0003#
9
ESR (mm)
20 (14–24)
14 (10–20)
0.07
10
FSH (IU/L)
5 (3.7–7)
4.7 (3.5–6.2)
< 0.0001$
11
LH (IU/L)
4.2 (2.8–6.3)
6.7 (5.1–8.3)
0.05*
12
LH/FSH
0.9 (0.5–1.5)
1.5 (1–2.1)
< 0.0001$
13
TSH (µIU/mL)
2 (1.6–3.4)
2.6 (1.9–3.8)
< 0.0001$
14
Progesterone (mol/L)
0.68 (0.42–1)
0.84 (0.60–1.3)
0.038*
15
Mg (mg/dL)
1.9 (1.8–2.2)
1.8 (1.3–2.3)
0.03*
16
Cp (IU/L)
1,140 (845–1,483)
1,420 (945–1,810)
0.0003#
17
AFC (n)
7 (6.2–8.2)
13 (11–17)
< 0.0001$
18
No mense in a year
13 (11–13)
8.2 (6.3–10)
< 0.0001$
Statistical analysis was performed using the GraphPad Prism 6.0. The continuous variables are expressed as mean ± SD; the significant differences obtained in PCOS subjects and controls were calculated and compared using ANOVA. *P value < 0.05 was considered to be statistically significant. Values are expressed *P < 0.05, #P <0.01, and $P < 0.001. 2-h PG: postload 2-hour glucose; FBS: fasting blood glucose; n: number; PRL: prolactin; Sl No.: serial number
The authors declare that they have no conflicts of interest.
Ethical approval
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the Declaration of Helsinki 1964 and its later amendments or comparable ethical standards. The study was approved by the institutional review committee of the Armed Forces Medical College, Pune reference number IEC/2018/23.
Consent to participate
Informed consent to participate in the study was obtained from all participants.
Consent to publication
Informed consent to publication was obtained from relevant participants.
Availability of data and materials
The data that support the findings of this study will be shared upon reasonable request data policy from the corresponding author.
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